Literature DB >> 25972651

Intracranial metastasis of adenocarcinoma of the prostate presenting with symptoms of spinal cord compression.

Rachael Hutton1, John Maguire1, Tarik Amer1, John Fitzpatrick1, Rami Hasan1, Mark Ablett1, Robert Meddings1.   

Abstract

Spinal cord compression is a not uncommon complication of metastatic prostate cancer. Intracranial metastasis of prostatic adenocarcinoma is however unusual. We report a case of a 67-year-old man with metastatic prostate carcinoma, who presented with a 3-day history of lower limb weakness and collapse. Neurological assessment demonstrated increased tone and reduced power in both legs. As he had typical signs and symptoms of spinal cord compression, an MRI of the spine was performed; this demonstrated no evidence of cord compression. A subsequent CT of the brain demonstrated an extensive parafalcine metastasis. This revealed an extensive enhancing mass extending bilaterally along almost the entire length of the falx cerebri, measuring up to 3 cm in width and associated with marked white matter oedema in the adjacent brain bilaterally. Unfortunately, this man succumbed to his illness a few days later. The imaging findings are presented and highlight the importance of brain imaging in patients presenting with suspected cord compression due to prostatic metastatic disease when MR of the spine shows no evidence of cord compression.

Entities:  

Keywords:  Intracranial metastases; Oncology; Prostate cancer; Spinal cord compression

Year:  2014        PMID: 25972651      PMCID: PMC4425781          DOI: 10.1007/s12262-014-1143-1

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  5 in total

Review 1.  Intracranial metastases as the first manifestation of prostate cancer.

Authors:  M A Sutton; H L Watkins; L K Green; D Kadmon
Journal:  Urology       Date:  1996-11       Impact factor: 2.649

2.  Dural prostate adenocarcinoma metastasis with subdural hematoma mimicking the appearance of an epidural hematoma.

Authors:  Michael J Dorsi; George Zenonos; Wesley Hsu; Judy Huang
Journal:  Clin Neurol Neurosurg       Date:  2010-03-27       Impact factor: 1.876

3.  Vanishing tumour of the internal auditory meatus.

Authors:  A Jain; M Ablett; P Wardrop
Journal:  J Laryngol Otol       Date:  2008-08-12       Impact factor: 1.469

4.  Brain metastasis from prostate carcinoma: The M. D. Anderson Cancer Center experience.

Authors:  Ivo W Tremont-Lukats; George Bobustuc; George K Lagos; Konstantinos Lolas; Athanassios P Kyritsis; Vinay K Puduvalli
Journal:  Cancer       Date:  2003-07-15       Impact factor: 6.860

5.  Transdural metastasis from adenocarcinoma of the prostate mimicking subdural hematoma: case report.

Authors:  Jeffrey M Tomlin; Cargill H Alleyne
Journal:  Surg Neurol       Date:  2002-11
  5 in total
  2 in total

Review 1.  Malignant invasion of the central nervous system: the hidden face of a poorly understood outcome of prostate cancer.

Authors:  Eliane Gouvêa de Oliveira Barros; Nathalia Meireles Da Costa; Celia Yelimar Palmero; Luis Felipe Ribeiro Pinto; Luiz Eurico Nasciutti; Antonio Palumbo
Journal:  World J Urol       Date:  2018-07-06       Impact factor: 4.226

2.  Prostate Adenocarcinoma with Brain Metastasis: A Surveillance, Epidemiology, and End Results Database Analysis 2010-2015.

Authors:  Zin W Myint; Ayman H Qasrawi
Journal:  Med Sci Monit       Date:  2021-04-12
  2 in total

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