Literature DB >> 25972030

Long-term outcomes and factors influencing late survival following elective abdominal aortic aneurysm repair: A 24-year experience.

Manar Khashram1, Julie S Jenkins2, Jason Jenkins2, Allan J Kruger2, Nicholas S Boyne2, Wallace J Foster2, Philip J Walker3.   

Abstract

BACKGROUND: Abdominal aortic aneurysms can be either treated by an open abdominal aortic aneurysm repair or an endovascular repair. Comparing clinical predictors of outcomes and those which influence survival rates in the long term is important in determining the choice of treatment offered and the decision-making process with patients. AIMS: To determine the influence of pre-existing clinical predictors and perioperative determinants on late survival of elective open abdominal aortic aneurysm repair and endovascular repair at a tertiary hospital.
METHODS: Consecutive patients undergoing elective abdominal aortic aneurysm repair from 1990 to 2013 were included. Data were collected from a prospectively acquired database and death data were gathered from the Queensland state death registry. Pre-existing risks and perioperative factors were assessed independently. Kaplan-Meier and Cox regression modeling were performed.
RESULTS: During the study period, 1340 abdominal aortic aneurysms were repaired electively, of which 982 were open abdominal aortic aneurysm repair. The average age was 72.4 years old and 81.7% were males. The cumulative percentage survival rates for open abdominal aortic aneurysms repair at 5, 10, 15 and 20 years were 79, 49, 31 and 22, respectively. The corresponding 5-, 10- and 15-year survival rates for endovascular repair were not significantly different at 75, 49 and 33%, respectively (P = 0.75). Predictors of reduced survival were advanced age, American Society of Anaesthesiology scores, chronic obstructive pulmonary disease, renal impairment, bifurcated grafts, peripheral vascular disease and congestive heart failure.
CONCLUSIONS: Open repair offers a good long-term treatment option for patients with an abdominal aortic aneurysm and in our experience there is no significant difference in late survival between open abdominal aortic aneurysms repair and endovascular repair. Consideration of the factors identified in this study that predict reduced long-term survival for open abdominal aortic aneurysms repair and endovascular repair should be considered when deciding repair of abdominal aortic aneurysm.
© The Author(s) 2015.

Entities:  

Keywords:  Abdominal aortic aneurysm repair; EVAR; model; open aortic repair; risk factors; survival

Mesh:

Year:  2015        PMID: 25972030     DOI: 10.1177/1708538115586682

Source DB:  PubMed          Journal:  Vascular        ISSN: 1708-5381            Impact factor:   1.285


  2 in total

1.  External validation of a 5-year survival prediction model after elective abdominal aortic aneurysm repair.

Authors:  Randall R DeMartino; Ying Huang; Jay Mandrekar; Philip P Goodney; Gustavo S Oderich; Manju Kalra; Thomas C Bower; Jack L Cronenwett; Peter Gloviczki
Journal:  J Vasc Surg       Date:  2017-08-12       Impact factor: 4.268

2.  What factors counteract mid-term survival following endovascular repair of abdominal aortic aneurysms?

Authors:  Ertekin Utku Ünal; Hakkı Zafer İscan; Bekir Bogachan Akkaya; İsa Civelek; Mehmet Karahan; Ece Celikten; Göktan Askin; Hayrettin Levent Mavioğlu; Mehmet Ali Özatik
Journal:  Kardiochir Torakochirurgia Pol       Date:  2021-05-15
  2 in total

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