Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Intranasal sumatriptan for migraine in children.

Literature DB >> 25971759

Intranasal sumatriptan for migraine in children.

Abstract

QUESTION: I am seeing more and more children and adolescents with headaches that can be defined as migraine headache. I have read about intranasal sumatriptan as an abortive therapy. Is this an effective treatment? ANSWER: Acute migraine headache among children and adolescents is common and treatment is challenging. Intranasal sumatriptan is a safe and mostly effective option for children and adolescents. Currently the recommended dose is 20 mg for children who weigh more than 40 kg and 10 mg for children who weigh between 20 and 39 kg. Larger trials should be conducted to overcome the limitations of small sample sizes, potential low plasma concentration, and placebo effects witnessed in studies to date. Copyright© the College of Family Physicians of Canada.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2015 PMID： 25971759 PMCID： PMC4430059

Source DB: PubMed Journal: Can Fam Physician ISSN： 0008-350X Impact factor: 3.275

24 in total

1. Intranasal sumatriptan for the acute treatment of migraine in children.

Authors: M A Ueberall; D Wenzel
Journal: Neurology Date: 1999-04-22 Impact factor: 9.910

Review 2. Intranasal sumatriptan: in adolescents with migraine.

Authors: Monique P Curran; Hannah C Evans; Antona J Wagstaff
Journal: CNS Drugs Date: 2005 Impact factor: 5.749

3. A randomized, double-blind, placebo-controlled study of sumatriptan nasal spray in the treatment of acute migraine in adolescents.

Authors: P Winner; A D Rothner; J Saper; R Nett; M Asgharnejad; A Laurenza; R Austin; M Peykamian
Journal: Pediatrics Date: 2000-11 Impact factor: 7.124

Review 4. Practice parameter: pharmacological treatment of migraine headache in children and adolescents: report of the American Academy of Neurology Quality Standards Subcommittee and the Practice Committee of the Child Neurology Society.

Authors: D Lewis; S Ashwal; A Hershey; D Hirtz; M Yonker; S Silberstein
Journal: Neurology Date: 2004-12-28 Impact factor: 9.910

Intranasal sumatriptan for migraine in children.

1. Intranasal sumatriptan for the acute treatment of migraine in children.

Review 2. Intranasal sumatriptan: in adolescents with migraine.

3. A randomized, double-blind, placebo-controlled study of sumatriptan nasal spray in the treatment of acute migraine in adolescents.

Review 4. Practice parameter: pharmacological treatment of migraine headache in children and adolescents: report of the American Academy of Neurology Quality Standards Subcommittee and the Practice Committee of the Child Neurology Society.

5. Preliminary brain-targeting studies on intranasal mucoadhesive microemulsions of sumatriptan.

6. Childhood migraine in general practice: clinical features and characteristics.

7. Quality of life in paediatric migraine: characterization of age-related effects using PedsQL 4.0.

8. Prevalence of headache and migraine in schoolchildren.

9. Nasal sumatriptan is effective in treatment of migraine attacks in children: A randomized trial.

Review 10. Clinical pharmacokinetics of intranasal sumatriptan.

1. Migraine treatment: a chain of adverse effects.