Literature DB >> 2597137

Enantiomeric selectivity of adenosine transport systems in mouse erythrocytes and L1210 cells.

W P Gati1, L Dagnino, A R Paterson.   

Abstract

In mediating the entry of adenosine into mouse erythrocytes and mouse leukaemia L1210 cells, nucleoside transport systems were stereoselective, showing a marked preference for the D-enantiomer of adenosine (D-Ado). Inward zero-trans fluxes of the mirror-image isomer, L-adenosine (L-Ado), in those cells were slow relative to those of D-Ado. Contributing to L-Ado fluxes in both cell types were (i) a transporter-mediated process of high nitrobenzylthioinosine-sensitivity and (ii) simple diffusion.

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Year:  1989        PMID： 2597137      PMCID： PMC1133523          DOI： 10.1042/bj2630957

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  Glucose transport in plasma membrane vesicles from rat adipose tissue.

Authors:  J R Carter; J Avruch; D B Martin
Journal:  J Biol Chem       Date:  1972-05-10       Impact factor: 5.157

2.  Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants.

Authors:  C E Cass; A R Paterson
Journal:  J Biol Chem       Date:  1972-05-25       Impact factor: 5.157

3.  Inhibitors of nucleoside transport. A structure-activity study using human erythrocytes.

Authors:  B Paul; M F Chen; A R Paterson
Journal:  J Med Chem       Date:  1975-10       Impact factor: 7.446

4.  Inward fluxes of adenosine in erythrocytes and cultured cells measured by a quenched-flow method.

Authors:  A R Paterson; E R Harley; C E Cass
Journal:  Biochem J       Date:  1984-12-15       Impact factor: 3.857

5.  Initial rate kinetics of the transport of adenosine and 4-amino-7-(beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine (tubercidin) in cultured cells.

Authors:  E R Harley; A R Paterson; C E Cass
Journal:  Cancer Res       Date:  1982-04       Impact factor: 12.701

6.  Species differences in nucleoside transport. A study of uridine transport and nitrobenzylthioinosine binding by mammalian erythrocytes.

Authors:  S M Jarvis; J R Hammond; A R Paterson; A S Clanachan
Journal:  Biochem J       Date:  1982-10-15       Impact factor: 3.857

7.  Studies on synthetic nucleotides. IV. Preparation of L-beta-ribonucleosides and L-beta-ribonucleotides.

Authors:  M Asai; H Hieda; B Shimizu
Journal:  Chem Pharm Bull (Tokyo)       Date:  1967-12       Impact factor: 1.645

8.  An assay for inhibitors of nucleoside transport based upon the use of 5-[125I]iodo-2'-deoxyuridine as permeant.

Authors:  W B Mahony; T P Zimmerman
Journal:  Anal Biochem       Date:  1986-04       Impact factor: 3.365

9.  Structural modifications at the 2'- and 3'-positions of some pyrimidine nucleosides as determinants of their interaction with the mouse erythrocyte nucleoside transporter.

Authors:  W P Gati; H K Misra; E E Knaus; L I Wiebe
Journal:  Biochem Pharmacol       Date:  1984-11-01       Impact factor: 5.858

10.  Plaque formation and isolation of pure lines with poliomyelitis viruses.

Authors:  R DULBECCO; M VOGT
Journal:  J Exp Med       Date:  1954-02       Impact factor: 14.307
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  3 in total

1.  Parasite-induced processes for adenosine permeation in mouse erythrocytes infected with the malarial parasite Plasmodium yoelii.

Authors:  W P Gati; A N Lin; T I Wang; J D Young; A R Paterson
Journal:  Biochem J       Date:  1990-11-15       Impact factor: 3.857

2.  Effects of transformation by v-fps on nucleoside transport in Rat-2 fibroblasts.

Authors:  K A Meckling-Gill; C E Cass
Journal:  Biochem J       Date:  1992-02-15       Impact factor: 3.857

3.  Intracellular metabolism of (-)- and (+)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in HepG2 derivative 2.2.15 (subclone P5A) cells.

Authors:  M T Paff; D R Averett; K L Prus; W H Miller; D J Nelson
Journal:  Antimicrob Agents Chemother       Date:  1994-06       Impact factor: 5.191
  3 in total

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