Literature DB >> 2597080

Measurement of regional cerebral blood flow and accentuation of the primary auditory cortex with single photon emission computed tomography.

A Schadel1, M Fischer.   

Abstract

Conventional brain scanning uses polar tracers which do not penetrate the normal blood-brain barrier. Radiolabeled amines like 123-iodoamphetamine (IMP) cross the barrier to inhibit serotonin and norepinephrine in synaptosomes. Studies of cerebral perfusion and function seem to be successful with such labeling. We advance the hypothesis for an increased IMP uptake in the stimulated primary auditory cortex. The method of single photon emission computed tomography (SPECT) is described. We have also been able to demonstrate marking of the primary auditory cortex by an increased amphetamine input in 6 out of 15 cases during stimulation by white noise.

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Year:  1989        PMID： 2597080     DOI： 10.1007/bf00453663

Source DB:  PubMed          Journal:  Arch Otorhinolaryngol        ISSN： 0302-9530


  12 in total

1.  Significance of radiocontaminants in 123I for dosimetry and scintillation camera imaging.

Authors:  G A Baker; D J Lum; E M Smith; H S Winchell
Journal:  J Nucl Med       Date:  1976-08       Impact factor: 10.057

2.  Initial experience with SPECT (single-photon computerized tomography) of the brain using N-isopropyl I-123 p-iodoamphetamine: concise communication.

Authors:  T C Hill; B L Holman; R Lovett; D H O'Leary; D Front; P Magistretti; R E Zimmerman; S Moore; M E Clouse; J L Wu; T H Lin; R M Baldwin
Journal:  J Nucl Med       Date:  1982-03       Impact factor: 10.057

3.  A refined method to relate morphological and functional aspects of aphasia.

Authors:  R Blunk; R De Bleser; K Willmes; H Zeumer
Journal:  Eur Neurol       Date:  1981       Impact factor: 1.710

4.  [Comparison of 133xenon and 123I-isopropylamphetamine for measuring regional cerebral circulation].

Authors:  J P Hedde; W Fiegler; S Schulz; W Christe; R Felix
Journal:  Rofo       Date:  1984-08

5.  [Cerebral emission computer tomography (SPECT) with 123I-labeled amphetamines].

Authors:  H J Biersack; H Penin; A Hartmann; K Reichmann; C Winkler
Journal:  Dtsch Med Wochenschr       Date:  1984-07-27       Impact factor: 0.628

6.  Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography.

Authors:  N A Lassen; L Henriksen; O Paulson
Journal:  Stroke       Date:  1981 May-Jun       Impact factor: 7.914

7.  Noninvasive tomographic study of cerebral blood flow and oxygen metabolism in vivo. Potentials, limitations, and clinical applications in cerebral ischemic disorders.

Authors:  J C Baron; M G Bousser; D Comar; F Soussaline; P Castaigne
Journal:  Eur Neurol       Date:  1981       Impact factor: 1.710

8.  Comparison of N-isopropyl (I-123) p-iodoamphetamine brain scans using Anger camera scintigraphy and single-photon emission tomography.

Authors:  R G Lee; T C Hill; B L Holman; R Uren; M E Clouse
Journal:  Radiology       Date:  1982-12       Impact factor: 11.105

9.  Dynamic SPECT with Xe-133: regional cerebral blood flow in patients with unilateral cerebrovascular disease: concise communication.

Authors:  U Buell; E A Moser; P Schmiedek; G Leinsinger; T Kreisig; C M Kirsch; K Einhäupl
Journal:  J Nucl Med       Date:  1984-04       Impact factor: 10.057

10.  N-isopropyl-[123I] p-iodoamphetamine: single-pass brain uptake and washout; binding to brain synaptosomes; and localization in dog and monkey brain.

Authors:  H S Winchell; W D Horst; L Braun; W H Oldendorf; R Hattner; H Parker
Journal:  J Nucl Med       Date:  1980-10       Impact factor: 10.057
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