Literature DB >> 25970577

Correction: The GATA Factor elt-1 Regulates C. elegans Developmental Timing by Promoting Expression of the let-7 Family MicroRNAs.

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Abstract

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Year:  2015        PMID: 25970577      PMCID: PMC4430550          DOI: 10.1371/journal.pgen.1005257

Source DB:  PubMed          Journal:  PLoS Genet        ISSN: 1553-7390            Impact factor:   5.917


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There are errors in Table 1. The trans-heterozygous genotypes under ‘’ are not displayed in the standard way; + should be ku491/+, + should be ok1002/+ and ok1002 should be ku491/ok1002. The correct table is displayed underneath.
Table 1

elt-1 mutants have an L4-stage bursting vulva and defective alae formation and elt-1(ku491) is a partial loss-of- function allele.

StrainRNAiL4 Bursting VulvaL4 Molt AlaeYoung Adult Seam Cells
%nAbsent (%)Gapped (%)Present (%)nSCMStd Devn
wild-typeEmpty vector a 0.02450.00.0100.02716.00.427
daf-12(rh61rh411) Empty vector a 0.01830.00.0100.02418.11.624
elt-1(ku491) Empty vector a 3.616988.43.87.62612.92.215
elt-1(ku491);daf-12(rh61rh411) Empty vector a 55.119888.80.011.11839.79.829
wild-type elt-1 48.7117100.00.00.0210.50.821
daf-12(rh61rh411) elt-1 56.79090.05.05.0200.20.420
elt-1(ku491) elt-1 76.3114100.00.00.0271.31.227
elt-1(ku491);daf-12(rh61rh411) elt-1 94.823196.43.60.0282.02.228
elt-1 genotype b daf-12 genotype
ku491/+ Wild-type 0.0600.00.0100.01915.90.318
ku491/+ rh61rh411 0.0570.00.0100.01818.31.818
ok1002/+ Wild-type 0.0920.00.0100.01816.00.318
ok1002/+ rh61rh411 0.0780.00.0100.01718.21.917
ku491/ok1002 Wild-type 1.95284.016.00.0259.4 c 2.025
ku491/ok1002 rh61rh411 65.941100.00.00.02018.2 d 6.620

aPhenotypes on empty-vector control RNAi were similar to the standard E. coli strain OP50.

bAn allele of elt-1(ku491) linked to mutations in unc-24 and dpy-20 was used for these strains.

cFor elt-1(ku491) animals vs elt-1(ku491)-over-elt-1(null) animals at the young adult stage, the p-value for the comparison of seam-cell numbers is 0.0340

dFor elt-1(ku491);daf-12(rh61rh411) animals vs elt-1(ku491)-over-elt-1(null);daf-12(rh61rh411) animals at the young adult stage, the p-value for the comparison of seam-cell numbers is < 0.0001.

aPhenotypes on empty-vector control RNAi were similar to the standard E. coli strain OP50. bAn allele of elt-1(ku491) linked to mutations in unc-24 and dpy-20 was used for these strains. cFor elt-1(ku491) animals vs elt-1(ku491)-over-elt-1(null) animals at the young adult stage, the p-value for the comparison of seam-cell numbers is 0.0340 dFor elt-1(ku491);daf-12(rh61rh411) animals vs elt-1(ku491)-over-elt-1(null);daf-12(rh61rh411) animals at the young adult stage, the p-value for the comparison of seam-cell numbers is < 0.0001.
  1 in total

1.  The GATA factor elt-1 regulates C. elegans developmental timing by promoting expression of the let-7 family microRNAs.

Authors:  Max L Cohen; Sunhong Kim; Kiyokazu Morita; Seong Heon Kim; Min Han
Journal:  PLoS Genet       Date:  2015-03-27       Impact factor: 5.917

  1 in total

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