Literature DB >> 25968135

Pre-clinical In Vitro and In Vivo Models for Heart Valve Therapies.

Maurizio Taramasso1, Maximilian Y Emmert, Diana Reser, Andrea Guidotti, Nikola Cesarovic, Marino Campagnol, Alessandro Addis, Fabian Nietlispach, Simon P Hoerstrup, Francesco Maisano.   

Abstract

Heart valve disease is a frequently encountered pathology, related to high morbidity and mortality rates. Animal models are interesting to investigate the causality but also underlying mechanisms and potential treatments of human heart valve diseases. Strongly believing that both in vivo and ex vivo models are fundamental to support research and development of new technologies, we here report some examples of heart valve disease models, which in our experience have been actively used to support the development of new valve therapies.

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Year:  2015        PMID： 25968135     DOI： 10.1007/s12265-015-9631-7

Source DB:  PubMed          Journal:  J Cardiovasc Transl Res        ISSN： 1937-5387            Impact factor:   4.132


  25 in total

1.  Minimally-invasive implantation of living tissue engineered heart valves: a comprehensive approach from autologous vascular cells to stem cells.

Authors:  Dörthe Schmidt; Petra E Dijkman; Anita Driessen-Mol; Rene Stenger; Christine Mariani; Arja Puolakka; Marja Rissanen; Thorsten Deichmann; Bernhard Odermatt; Benedikt Weber; Maximilian Y Emmert; Gregor Zund; Frank P T Baaijens; Simon P Hoerstrup
Journal:  J Am Coll Cardiol       Date:  2010-08-03       Impact factor: 24.094

Review 2.  Evolving concepts of cardiac valve dynamics: the continuum of development, functional structure, pathobiology, and tissue engineering.

Authors:  Frederick J Schoen
Journal:  Circulation       Date:  2008-10-28       Impact factor: 29.690

3.  Transcatheter implantation of homologous "off-the-shelf" tissue-engineered heart valves with self-repair capacity: long-term functionality and rapid in vivo remodeling in sheep.

Authors:  Anita Driessen-Mol; Maximilian Y Emmert; Petra E Dijkman; Laura Frese; Bart Sanders; Benedikt Weber; Nikola Cesarovic; Michele Sidler; Jori Leenders; Rolf Jenni; Jürg Grünenfelder; Volkmar Falk; Frank P T Baaijens; Simon P Hoerstrup
Journal:  J Am Coll Cardiol       Date:  2013-12-18       Impact factor: 24.094

4.  Injectable living marrow stromal cell-based autologous tissue engineered heart valves: first experiences with a one-step intervention in primates.

Authors:  Benedikt Weber; Jacques Scherman; Maximilian Y Emmert; Juerg Gruenenfelder; Renier Verbeek; Mona Bracher; Melanie Black; Jeroen Kortsmit; Thomas Franz; Roman Schoenauer; Laura Baumgartner; Chad Brokopp; Irina Agarkova; Petra Wolint; Gregor Zund; Volkmar Falk; Peter Zilla; Simon P Hoerstrup
Journal:  Eur Heart J       Date:  2011-03-17       Impact factor: 29.983

5.  Mitral annular reduction with subablative therapeutic ultrasound: pre-clinical evaluation of the ReCor device.

Authors:  Hasan Jilaihawi; Renu Virmani; Hiroshi Nakagawa; Anique Ducharme; Yan-Fen Shi; Naima Carter-Monroe; Elena Ladich; Mano Iyer; Atsushi Ikeda; Anita Asgar; Raoul Bonan
Journal:  EuroIntervention       Date:  2010-05       Impact factor: 6.534

Review 6.  Tissue engineering.

Authors:  R Langer; J P Vacanti
Journal:  Science       Date:  1993-05-14       Impact factor: 47.728

7.  Stem cell-based transcatheter aortic valve implantation: first experiences in a pre-clinical model.

Authors:  Maximilian Y Emmert; Benedikt Weber; Petra Wolint; Luc Behr; Sebastien Sammut; Thomas Frauenfelder; Laura Frese; Jacques Scherman; Chad E Brokopp; Christian Templin; Jürg Grünenfelder; Gregor Zünd; Volkmar Falk; Simon P Hoerstrup
Journal:  JACC Cardiovasc Interv       Date:  2012-08       Impact factor: 11.195

8.  Off-the-shelf human decellularized tissue-engineered heart valves in a non-human primate model.

Authors:  Benedikt Weber; Petra E Dijkman; Jacques Scherman; Bart Sanders; Maximilian Y Emmert; Jürg Grünenfelder; Renier Verbeek; Mona Bracher; Melanie Black; Thomas Franz; Jeroen Kortsmit; Peter Modregger; Silvia Peter; Marco Stampanoni; Jérôme Robert; Debora Kehl; Marina van Doeselaar; Martin Schweiger; Chad E Brokopp; Thomas Wälchli; Volkmar Falk; Peter Zilla; Anita Driessen-Mol; Frank P T Baaijens; Simon P Hoerstrup
Journal:  Biomaterials       Date:  2013-06-28       Impact factor: 12.479

Review 9.  Transcatheter tissue engineered heart valves.

Authors:  Maximilian Y Emmert; Benedikt Weber; Volkmar Falk; Simon P Hoerstrup
Journal:  Expert Rev Med Devices       Date:  2013-11-26       Impact factor: 3.166

Review 10.  Heart valve tissue engineering: concepts, approaches, progress, and challenges.

Authors:  Karen Mendelson; Frederick J Schoen
Journal:  Ann Biomed Eng       Date:  2006-10-12       Impact factor: 3.934
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  3 in total

Review 1.  Translational Challenges in Cardiovascular Tissue Engineering.

Authors:  Maximilian Y Emmert; Emanuela S Fioretta; Simon P Hoerstrup
Journal:  J Cardiovasc Transl Res       Date:  2017-03-09       Impact factor: 4.132

2.  The characteristics of a porcine mitral regurgitation model.

Authors:  Bo Li; Yongchun Cui; Dong Zhang; Xiaokang Luo; Fuliang Luo; Bin Li; Yue Tang
Journal:  Exp Anim       Date:  2018-05-22

3.  Ex Vivo Model of Functional Mitral Regurgitation Using Deer Hearts.

Authors:  Michal Jaworek; Andrea Mangini; Edoardo Maroncelli; Federico Lucherini; Rubina Rosa; Eleonora Salurso; Emiliano Votta; Carlo Antona; Gianfranco Beniamino Fiore; Riccardo Vismara
Journal:  J Cardiovasc Transl Res       Date:  2020-09-21       Impact factor: 4.132
  3 in total

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