Literature DB >> 25965116

Protective effects of Nitraria retusa extract and its constituent isorhamnetin against amyloid β-induced cytotoxicity and amyloid β aggregation.

Akihisa Iida1, Takeo Usui, Feten Zar Kalai, Junkyu Han, Hiroko Isoda, Yoko Nagumo.   

Abstract

Nitraria retusa is a halophyte species that is distributed in North Africa and used as a traditional medicinal plant. In this study, N. retusa ethanol extract and its constituent isorhamnetin (IRA) protected against amyloid β (Aβ)-induced cytotoxicity in human neuroblastoma SH-SY5Y cells. An in vitro Aβ aggregation assay suggested that IRA destabilizes Aβ fibrils.

Entities:  

Keywords:  Alzheimer’s disease; amyloid β; isorhamnetin

Mesh：

Substances：

Year:  2015        PMID： 25965116     DOI： 10.1080/09168451.2015.1027655

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  4 in total

1.  Chromone-lipoic acid conjugate: Neuroprotective agent having acceptable butyrylcholinesterase inhibition, antioxidant and copper-chelation activities.

Authors:  Leili Jalili-Baleh; Hamid Nadri; Hamid Forootanfar; Tuba Tüylü Küçükkılınç; Beyza Ayazgök; Mohammad Sharifzadeh; Mahban Rahimifard; Maryam Baeeri; Mohammad Abdollahi; Alireza Foroumadi; Mehdi Khoobi
Journal:  Daru       Date:  2021-01-09       Impact factor: 3.117

2.  Flavonoids for treatment of Alzheimer's disease: An up to date review.

Authors:  Jae Kwang Kim; Sang Un Park
Journal:  EXCLI J       Date:  2021-02-26       Impact factor: 4.068

3.  Network Pharmacology-Based Study of the Underlying Mechanisms of Huangqi Sijunzi Decoction for Alzheimer's Disease.

Authors:  Wei Zhang; Mingti Lv; Yating Shi; Yonghui Mu; Zhaoyang Yao; Zhijun Yang
Journal:  Evid Based Complement Alternat Med       Date:  2021-10-05       Impact factor: 2.629

4.  Isorhamnetin Attenuated the Release of Interleukin-6 from β-Amyloid-Activated Microglia and Mitigated Interleukin-6-Mediated Neurotoxicity.

Authors:  Pei-Cih Wei; Guey-Jen Lee-Chen; Chiung-Mei Chen; Ying Chen; Yen-Shi Lo; Kuo-Hsuan Chang
Journal:  Oxid Med Cell Longev       Date:  2022-09-15       Impact factor: 7.310
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.