Carmen Stromberger1, Waldemar Wlodarczyk2, Simone Marnitz2, Basil Jamil3, Volker Budach2, Jan-Dirk Raguse4, Arne Boettcher5, Harun Badakhshi2. 1. Department of Radiation Oncology and Radiotherapy, Charité Universitaetsmedizin Berlin, Berlin, Germany carmen.stromberger@charite.de. 2. Department of Radiation Oncology and Radiotherapy, Charité Universitaetsmedizin Berlin, Berlin, Germany. 3. Praxis für Strahlentherapie, Klinikum Frankfurt Oder, Frankfurt, Germany. 4. Department of Oral and Maxillofacial Surgery, Charité Universitaetsmedizin Berlin, Berlin, Germany. 5. Department of Otorhinolaryngology, Charité Universitaetsmedizin Berlin, Berlin, Germany.
Abstract
AIM: The aim of the present study was to compare simultaneous integrated boost (SIB) plans using volumetric modulated arc therapy (RapidArc®; RA) or tomotherapy (TT) for bilateral (BL) and unilateral (UL) treatment in head-and-neck cancer (HNC) patients. MATERIAL AND METHODS: Seventeen computed tomography scans (CTs) of 16 patients with SIB were replanned using TT and RA. We defined three groups: All, UL and BL, compared the dose distributions, homogeneity, conformity to planning target volume (PTV), organs at risk (OAR) and healthy tissue (HT) sparing. We evaluated a therapeutic-width index (TWI) based on PTV coverage and parotid gland (PG) sparing. RESULTS: PTV coverage for RA and TT was equivalent for all groups. UL irradiation resulted in similar doses to the HT for both techniques but TT achieved better sparing of spinal cord, larynx and contralateral PGs. TT provided better homogeneity. RA gave better conformity. CONCLUSION: Both methods achieved clinically acceptable results for UL and BL treatment, RA with better dose conformity to elective PTV, TT with better OAR sparing and homogeneity. Copyright
AIM: The aim of the present study was to compare simultaneous integrated boost (SIB) plans using volumetric modulated arc therapy (RapidArc®; RA) or tomotherapy (TT) for bilateral (BL) and unilateral (UL) treatment in head-and-neck cancer (HNC) patients. MATERIAL AND METHODS: Seventeen computed tomography scans (CTs) of 16 patients with SIB were replanned using TT and RA. We defined three groups: All, UL and BL, compared the dose distributions, homogeneity, conformity to planning target volume (PTV), organs at risk (OAR) and healthy tissue (HT) sparing. We evaluated a therapeutic-width index (TWI) based on PTV coverage and parotid gland (PG) sparing. RESULTS:PTV coverage for RA and TT was equivalent for all groups. UL irradiation resulted in similar doses to the HT for both techniques but TT achieved better sparing of spinal cord, larynx and contralateral PGs. TT provided better homogeneity. RA gave better conformity. CONCLUSION: Both methods achieved clinically acceptable results for UL and BL treatment, RA with better dose conformity to elective PTV, TT with better OAR sparing and homogeneity. Copyright
Authors: Steffi U Pigorsch; Severin Kampfer; Markus Oechsner; Michael C Mayinger; Petra Mozes; Michal Devecka; Kerstin K Kessel; Stephanie E Combs; Jan J Wilkens Journal: Radiat Oncol Date: 2020-11-02 Impact factor: 3.481