| Literature DB >> 25964134 |
Lillian M Lai1, M Beth McCarville2, Patricia Kirby3, Simon C S Kao4, Toshio Moritani4, Eve Clark4, Kousei Ishigami4, Armita Bahrami5, Yutaka Sato4.
Abstract
Inflammatory pseudotumor is a generic term used to designate a heterogeneous group of inflammatory mass-forming lesions histologically characterized by myofibroblastic proliferation with chronic inflammatory infiltrate. Inflammatory pseudotumor is multifactorial in etiology and generally benign, but it is often mistaken for malignancy given its aggressive appearance. It can occur throughout the body and is seen in all age groups. Inflammatory pseudotumor has been described in the literature by many organ-specific names, resulting in confusion. Recently within this generic category of inflammatory pseudotumor, inflammatory myofibroblastic tumor has emerged as a distinct entity and is now recognized as a fibroblastic/myofibroblastic neoplasm with intermediate biological potential and occurring mostly in children. We present interesting pediatric cases of inflammatory myofibroblastic tumors given this entity's tendency to occur in children. Familiarity and knowledge of the imaging features of inflammatory pseudotumor can help in making an accurate diagnosis, thereby avoiding unnecessary radical surgery.Entities:
Keywords: Children; Computed tomography; Inflammatory myofibroblastic tumor; Inflammatory pseudotumor; Magnetic resonance imaging; pediatric fibrous tumor
Mesh:
Year: 2015 PMID: 25964134 DOI: 10.1007/s00247-015-3360-6
Source DB: PubMed Journal: Pediatr Radiol ISSN: 0301-0449