Literature DB >> 25960821

Complex Psychiatric Comorbidity of Treatment-Seeking Youth With Autism Spectrum Disorder and Anxiety Symptoms.

Susan L Hepburn1, Jessica A Stern2, Audrey Blakeley-Smith2, Lila K Kimel3, Judith A Reaven4.   

Abstract

Anxiety disorders and other co-occurring psychiatric disorders significantly impact adaptive functioning for many children with autism spectrum disorder (ASD). This descriptive study examines the complexity of psychiatric comorbidity in treatment-seeking youth with ASD and anxiety symptoms. Forty-two parents of 8- to 14-year-old children with ASD and anxiety symptoms completed a structured psychiatric interview (K-SADS) and provided information about the child's past and current psychological functioning as part of a screening process to enter an anxiety intervention program. Overall, comorbidity was very complex, with children obtaining an average of 4 psychiatric diagnoses (including anxiety disorders) on a structured clinical interview (range = 0-9). Onset and course differed by psychiatric disorder. Complexity of comorbidity did not differ significantly by age, sex, or autism severity. Despite clinical significance of the symptoms reported, few children were currently (or ever) engaged in mental health treatment or group psychosocial intervention. Although the specificity of the current sample limits the generalizability of these results, findings suggest that treatment-seeking children with ASD and anxiety often present with additional psychiatric symptoms, which supports a transdiagnostic approach to research and intervention in this area. Accurate assessment of comorbidity may provide valuable information for families and clinicians regarding individualized treatment approaches.

Entities:  

Keywords:  anxiety; autism; descriptive; psychiatric comorbidity

Year:  2014        PMID: 25960821      PMCID: PMC4422383          DOI: 10.1080/19315864.2014.932476

Source DB:  PubMed          Journal:  J Ment Health Res Intellect Disabil        ISSN: 1931-5872


  23 in total

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Journal:  World J Biol Psychiatry       Date:  2010-08-24       Impact factor: 4.132

2.  Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.

Authors:  Denis G Sukhodolsky; Lawrence Scahill; Kenneth D Gadow; L Eugene Arnold; Michael G Aman; Christopher J McDougle; James T McCracken; Elaine Tierney; Susan Williams White; Luc Lecavalier; Benedetto Vitiello
Journal:  J Abnorm Child Psychol       Date:  2007-08-03

3.  Treating anxiety disorders in children with high functioning autism spectrum disorders: a controlled trial.

Authors:  Anne Marie Chalfant; Ron Rapee; Louisa Carroll
Journal:  J Autism Dev Disord       Date:  2006-12-15

4.  Psychopathology in children and adolescents with autism compared to young people with intellectual disability.

Authors:  Avril V Brereton; Bruce J Tonge; Stewart L Einfeld
Journal:  J Autism Dev Disord       Date:  2006-10

5.  Anxiety and social worries in children with Asperger syndrome.

Authors:  Emily Russell; Kate Sofronoff
Journal:  Aust N Z J Psychiatry       Date:  2005-07       Impact factor: 5.744

6.  The heavy burden of psychiatric comorbidity in youth with autism spectrum disorders: a large comparative study of a psychiatrically referred population.

Authors:  Gagan Joshi; Carter Petty; Janet Wozniak; Aude Henin; Ronna Fried; Maribel Galdo; Meghan Kotarski; Sarah Walls; Joseph Biederman
Journal:  J Autism Dev Disord       Date:  2010-11

7.  Comorbid psychiatric disorders in children with autism: interview development and rates of disorders.

Authors:  Ovsanna T Leyfer; Susan E Folstein; Susan Bacalman; Naomi O Davis; Elena Dinh; Jubel Morgan; Helen Tager-Flusberg; Janet E Lainhart
Journal:  J Autism Dev Disord       Date:  2006-10

8.  A randomised controlled trial of a CBT intervention for anxiety in children with Asperger syndrome.

Authors:  Kate Sofronoff; Tony Attwood; Sharon Hinton
Journal:  J Child Psychol Psychiatry       Date:  2005-11       Impact factor: 8.982

9.  High rates of psychiatric co-morbidity in PDD-NOS.

Authors:  Esther I de Bruin; Robert F Ferdinand; Sjifra Meester; Pieter F A de Nijs; Fop Verheij
Journal:  J Autism Dev Disord       Date:  2007-05

10.  Kiddie-SADS reveals high rates of DSM-IV disorders in children and adolescents with autism spectrum disorders.

Authors:  Elen Gjevik; Sigmund Eldevik; Torill Fjæran-Granum; Eili Sponheim
Journal:  J Autism Dev Disord       Date:  2011-06
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  6 in total

Review 1.  Psychosocial Treatments Targeting Anxiety and Depression in Adolescents and Adults on the Autism Spectrum: Review of the Latest Research and Recommended Future Directions.

Authors:  Susan W White; Grace Lee Simmons; Katherine O Gotham; Caitlin M Conner; Isaac C Smith; Kelly B Beck; Carla A Mazefsky
Journal:  Curr Psychiatry Rep       Date:  2018-08-28       Impact factor: 5.285

2.  Comprehensive Description of Comorbidity for Autism Spectrum Disorder in a General Population.

Authors:  David Cawthorpe
Journal:  Perm J       Date:  2017

3.  Emotional and behavioural problems of children with autism spectrum disorder attending mainstream schools.

Authors:  Stephanie E Hastings; Richard P Hastings; Michaela A Swales; J Carl Hughes
Journal:  Int J Dev Disabil       Date:  2021-01-05

4.  The Stability of Comorbid Psychiatric Disorders: A 7 Year Follow Up of Children with Pervasive Developmental Disorder-Not Otherwise Specified.

Authors:  C Verheij; A Louwerse; J van der Ende; M L J M Eussen; A R Van Gool; F Verheij; F C Verhulst; K Greaves-Lord
Journal:  J Autism Dev Disord       Date:  2015-12

5.  Pharmacogenomic testing: aiding in the management of psychotropic therapy for adolescents with autism spectrum disorders.

Authors:  Seuli Bose-Brill; Jinming Xing; Debra J Barnette; Christopher Hanks
Journal:  Pharmgenomics Pers Med       Date:  2017-09-25

6.  Oxytocin Differentiated Effects According to the Administration Route in a Prenatal Valproic Acid-Induced Rat Model of Autism.

Authors:  Radu Lefter; Alin Ciobica; Iulia Antioch; Daniela Carmen Ababei; Luminita Hritcu; Alina-Costina Luca
Journal:  Medicina (Kaunas)       Date:  2020-05-29       Impact factor: 2.430

  6 in total

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