Literature DB >> 25959530

Axillary lymphatic malformations: Prenatal evaluation and postnatal outcomes.

Aliza Olive1, Julie S Moldenhauer1, Pablo Laje1, Mark P Johnson1, Beverly G Coleman1, Teresa Victoria1, Alan W Flake1, N Scott Adzick2.   

Abstract

BACKGROUND/
PURPOSE: The purpose of this study is to describe the prenatal findings and postnatal outcomes of fetuses with axillary lymphatic malformations.
METHODS: Retrospective chart review of fetuses with the prenatal diagnosis of isolated axillary lymphatic malformation detected between 2009 and 2013.
RESULTS: There were 8 fetuses diagnosed with isolated axillary lymphatic malformation. Median gestational age at diagnosis was 20.5 (19-28) weeks. All fetuses were evaluated by serial ultrasound and ultrafast fetal MRI. Two pregnancies were electively terminated. All continued pregnancies reached term, and all fetuses were delivered by cesarean section. None of the fetuses developed polyhydramnios or hydrops fetalis. Only one patient had an associated malformation (coarctation of the aorta). All patients were evaluated postnatally by MRI. Treatment included sclerotherapy only (1), sclerotherapy followed by surgical resection (1), surgical resection only (3), and observation (1). The median postnatal hospital stay was 8 (6-15) days. Three cases recurred after the initial treatment, two after surgery and one after sclerotherapy. On a median follow up of 2.1 years, all patients have some degree of visible residual disease. There were no deaths.
CONCLUSIONS: Prenatal diagnosis of axillary lymphatic malformation is increasing with improved technology. Axillary lymphatic malformations are usually isolated developmental anomalies that do not affect fetal health. Postnatal management options include surgery, sclerotherapy, and observation. Recurrences and residual disease after all types of treatment are frequent. This should be communicated to the parents at the time of prenatal counseling.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  axillary lymphatic malformation; prenatal diagnosis; sclerotherapy

Mesh:

Year:  2015        PMID: 25959530     DOI: 10.1016/j.jpedsurg.2015.03.066

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  1 in total

1.  Contribution of magnetic resonance imaging to the prenatal diagnosis of common congenital vascular anomalies.

Authors:  Laurence Crivelli; Anne-Elodie Millischer; Pascale Sonigo; David Grévent; Sylviane Hanquinet; Yvan Vial; Leonor Alamo
Journal:  Pediatr Radiol       Date:  2021-04-23
  1 in total

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