Literature DB >> 25958062

Creation and validation of a condition-specific venous thromboembolism risk assessment tool for ventral hernia repair.

Christopher J Pannucci1, Marten N Basta2, John P Fischer2, Stephen J Kovach2.   

Abstract

BACKGROUND: We used the database of the American College of Surgeons National Surgical Quality Improvement Program to (1) identify risk factors for 30-day venous thromboembolism (VTE) after ventral hernia repair (VHR) and (2) to create and validate a condition-specific assessment tool for the risk of VTE.
METHODS: Open and laparoscopic VHR patients in the American College of Surgeons National Surgical Quality Improvement Program were identified using Current Procedural Terminology code. The occurrence of VTE, including deep-venous thrombosis (DVT) or pulmonary embolus, within 30 days postoperatively was the primary outcome. Regression-based analysis and subsequent bootstrap analysis created a weighted VTE risk assessment model (RAM) for ventral hernia repair. The weighted RAM was used to risk-stratify patients for both 30-day VTE risk and 30-day risk for medical and surgical complications.
RESULTS: Data for 113,873 hernia repair patients were obtained; 30-day deep-venous thrombosis, pulmonary embolus, and VTE rates were 0.59%, 0.43%, and 0.92%, respectively. The average time to VTE was 10.8 days. A 14-factor, weighted RAM was created. The weighted risk score identified a 25-fold variability (from 0.20 to 4.97%) in VTE risk among the overall VHR population. Although created to risk-stratify for VTE, the risk score also risk-stratified for 30-day medical and surgical complications, inpatient duration of stay, and 30-day mortality.
CONCLUSION: The 30-day VTE risk after VHR is 0.92%, but a 25-fold variability in VTE risk exists among the overall hernia population. We demonstrate that a weighted VTE RAM quantifies VTE risk among the population undergoing ventral hernia repair, and that VTE risk score can also be used to risk-stratify for 30-day medical and surgical complications as well as mortality.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2015        PMID: 25958062     DOI: 10.1016/j.surg.2015.04.001

Source DB:  PubMed          Journal:  Surgery        ISSN: 0039-6060            Impact factor:   3.982


  4 in total

1.  Coagulation and deep vein flow changes following laparoscopic total extraperitoneal inguinal hernia repair: a single-center, prospective cohort study.

Authors:  Chengguang Yang; Leiming Zhu
Journal:  Surg Endosc       Date:  2019-02-11       Impact factor: 4.584

2.  Comment to: sudden death caused by acute pulmonary embolism after laparoscopic total extraperitoneal inguinal hernia repair: a case report and literature review. C. Yang, L. Zhu.

Authors:  S Yasri; V Wiwanitkit
Journal:  Hernia       Date:  2017-04-13       Impact factor: 4.739

3.  Prediction Model of in-Hospital Venous Thromboembolism in Chinese Adult Patients after Hernia Surgery: The CHAT Score.

Authors:  Zhi-Chun Gu; Chi Zhang; Ya Yang; Ming-Gang Wang; Hang-Yu Li; Guang-Yong Zhang
Journal:  Clin Appl Thromb Hemost       Date:  2021 Jan-Dec       Impact factor: 2.389

4.  Extended-duration thromboprophylaxis after ventral hernia repair: a risk model to predict venous thrombotic events after hospital discharge.

Authors:  S B Kumar; D Mettupalli; J T Carter
Journal:  Hernia       Date:  2021-08-15       Impact factor: 2.920

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.