| Literature DB >> 25957898 |
Valeria V Orlova1, Christine L Mummery2.
Abstract
In a recent issue of Cell, Theodoris et al. (2015) used a complex systems biology approach to model vascular aortic calcification caused by mutations in the NOTCH1 gene. Comparison of endothelial cells from patient hiPSCs and genetically matched controls under fluid flow revealed novel mechanisms underlying the disease.Entities:
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Year: 2015 PMID： 25957898 DOI： 10.1016/j.stem.2015.04.006
Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633