Literature DB >> 25957692

SnapShot: Insulin/IGF1 Signaling.

David K G Ma1, Christian Stolte2, James R Krycer3, David E James4, Seán I O'Donoghue5.   

Abstract

The insulin/IGF1signaling pathway (ISP) plays an essential role in long-term health. Some perturbations in this pathway are associated with diseases such as type 2 diabetes; other perturbations extend lifespan in worms, flies, and mice. The ISP regulates many biological processes, including energy storage, apoptosis, transcription, and cellular homeostasis. Such regulation involves precise rewiring of temporal events in protein phosphorylation networks. For an animated version of this Enhanced SnapShot, please visit http://www.cell.com/cell/enhanced/odonoghue.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 25957692     DOI： 10.1016/j.cell.2015.04.041

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  6 in total

1.  Insulin signaling requires glucose to promote lipid anabolism in adipocytes.

Authors:  James R Krycer; Lake-Ee Quek; Deanne Francis; Armella Zadoorian; Fiona C Weiss; Kristen C Cooke; Marin E Nelson; Alexis Diaz-Vegas; Sean J Humphrey; Richard Scalzo; Akiyoshi Hirayama; Satsuki Ikeda; Futaba Shoji; Kumi Suzuki; Kevin Huynh; Corey Giles; Bianca Varney; Shilpa R Nagarajan; Andrew J Hoy; Tomoyoshi Soga; Peter J Meikle; Gregory J Cooney; Daniel J Fazakerley; David E James
Journal:  J Biol Chem       Date:  2020-07-28       Impact factor: 5.157

2.  A Novel SNP in the Promoter Region of IGF1 Associated With Yunshang Black Goat Kidding Number via Promoting Transcription Activity by SP1.

Authors:  Kunyu Li; Yufang Liu; Xiaoyun He; Lin Tao; Yanting Jiang; Rong Lan; Qionghua Hong; Mingxing Chu
Journal:  Front Cell Dev Biol       Date:  2022-05-12

3.  CellMap visualizes protein-protein interactions and subcellular localization.

Authors:  Christian Dallago; Tatyana Goldberg; Miguel Angel Andrade-Navarro; Gregorio Alanis-Lobato; Burkhard Rost
Journal:  F1000Res       Date:  2017-10-11

4.  Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin.

Authors:  Lake-Ee Quek; James R Krycer; Satoshi Ohno; Katsuyuki Yugi; Daniel J Fazakerley; Richard Scalzo; Sarah D Elkington; Ziwei Dai; Akiyoshi Hirayama; Satsuki Ikeda; Futaba Shoji; Kumi Suzuki; Jason W Locasale; Tomoyoshi Soga; David E James; Shinya Kuroda
Journal:  iScience       Date:  2020-01-21

5.  Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish.

Authors:  Ningmei Zeng; Jiankang Bao; TingTing Shu; Chuang Shi; Gang Zhai; Xia Jin; Jiangyan He; Qiyong Lou; Zhan Yin
Journal:  Front Endocrinol (Lausanne)       Date:  2022-07-29       Impact factor: 6.055

6.  Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology.

Authors:  Anup Ramachandran; Hartmut Jaeschke
Journal:  J Clin Transl Res       Date:  2017-02-12
  6 in total

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