Yilong Wang1, Xingquan Zhao2, Yong Jiang2, Hao Li2, Limin Wang2, S Claiborne Johnston2, Liping Liu2, Ka Sing Lawrence Wong2, Chunxue Wang2, Yuesong Pan2, Jing Jing2, Jie Xu2, Xia Meng2, Mei Zhang2, Yichong Li2, Yong Zhou2, Wenhua Zhao2, Yongjun Wang1. 1. From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. yongjunwang1962@gmail.com yilong528@gmail.com. 2. From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
Abstract
OBJECTIVES: To investigate the prevalence, knowledge, and treatment of TIA in a Chinese adult population. METHODS: We conducted a complex, multistage, probability sampling-designed, cross-sectional, nationwide survey of 98,658 Chinese adults in 2010. Possible TIA cases were first identified by symptoms recall or self-reported history of TIA through face-to-face interviews, and the final diagnosis was then made by expert neurologists through phone interviews or record review. RESULTS: The age-standardized prevalence of TIA was 2.27%. Clinically, only 16.0% of the participants were diagnosed before the study. The prevalence of TIA was higher in women and in patients who were older, had less education, were current smokers, lived in rural or undeveloped areas, and had a history of stroke, hypertension, myocardial infarction, dyslipidemia, or diabetes. Based on the survey responses, approximately 3.08% of Chinese adults had knowledge of TIA. Among patients with TIA, only 5.02% received treatment and 4.07% received guideline-recommended therapy. CONCLUSIONS: TIA is prevalent and an estimated 23.9 million people in China may have experienced a TIA. Public knowledge on TIA is very limited. TIA appears to be largely undiagnosed and untreated in China. There is an urgent need to develop strategies to improve the identification and appropriate management of TIA.
OBJECTIVES: To investigate the prevalence, knowledge, and treatment of TIA in a Chinese adult population. METHODS: We conducted a complex, multistage, probability sampling-designed, cross-sectional, nationwide survey of 98,658 Chinese adults in 2010. Possible TIA cases were first identified by symptoms recall or self-reported history of TIA through face-to-face interviews, and the final diagnosis was then made by expert neurologists through phone interviews or record review. RESULTS: The age-standardized prevalence of TIA was 2.27%. Clinically, only 16.0% of the participants were diagnosed before the study. The prevalence of TIA was higher in women and in patients who were older, had less education, were current smokers, lived in rural or undeveloped areas, and had a history of stroke, hypertension, myocardial infarction, dyslipidemia, or diabetes. Based on the survey responses, approximately 3.08% of Chinese adults had knowledge of TIA. Among patients with TIA, only 5.02% received treatment and 4.07% received guideline-recommended therapy. CONCLUSIONS:TIA is prevalent and an estimated 23.9 million people in China may have experienced a TIA. Public knowledge on TIA is very limited. TIA appears to be largely undiagnosed and untreated in China. There is an urgent need to develop strategies to improve the identification and appropriate management of TIA.
Authors: Evan L Thacker; Kerri L Wiggins; Kenneth M Rice; W T Longstreth; Joshua C Bis; Sascha Dublin; Nicholas L Smith; Susan R Heckbert; Bruce M Psaty Journal: Stroke Date: 2009-12-03 Impact factor: 7.914
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