Literature DB >> 25957245

[Sleep disorders in dementia patients].

E Savaskan1.   

Abstract

Dementia is characterized by cognitive and also behavioral and psychological symptoms of dementia (BPSD). The most prominent BPSD are depression and apathy but sleep disorders also complicate the clinical course of dementia. These symptoms are a severe burden for patients and caregivers and are difficult to treat partly due to comorbidities. Common sleep disorders in dementia are insomnia, hypersomnia, circadian rhythm alterations and aberrant nocturnal motor behavior. Sleep duration and rapid eye movement (REM) sleep are reduced. The diagnostic assessment of sleep disorders should include an evaluation of the underlying risk factors and a detailed sleep history for which several assessment instruments are available. The therapy of sleep disorders of dementia is primarily nonpharmacological: sleep counseling, sleep hygiene regulation, relaxation and psychotherapy techniques are given priority. Pharmacological treatment often has severe side effects in this elderly, vulnerable population and can only be considered if other nonpharmacological options have been unsuccessful. The application of medication should be limited in time and dosage. The pharmacological therapeutic options are critically discussed in detail.

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Year:  2015        PMID: 25957245     DOI: 10.1007/s00391-015-0890-3

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  21 in total

Review 1.  Treatment of sleep disturbance in Alzheimer's dementia.

Authors:  Oludamilola Salami; Constantine Lyketsos; Vani Rao
Journal:  Int J Geriatr Psychiatry       Date:  2010-09-24       Impact factor: 3.485

Review 2.  Sleep disturbances in Alzheimer's and Parkinson's diseases.

Authors:  Sarah M Rothman; Mark P Mattson
Journal:  Neuromolecular Med       Date:  2012-05-03       Impact factor: 3.843

Review 3.  Dementia and sleep.

Authors:  Heidi L Roth
Journal:  Neurol Clin       Date:  2012-11       Impact factor: 3.806

Review 4.  [Recommendations for diagnosis and therapy of behavioral and psychological symptoms in dementia (BPSD)].

Authors:  Egemen Savaskan; Irene Bopp-Kistler; Markus Buerge; Regina Fischlin; Dan Georgescu; Umberto Giardini; Martin Hatzinger; Ulrich Hemmeter; Isabella Justiniano; Reto W Kressig; Andreas Monsch; Urs P Mosimann; Renè Mueri; Anna Munk; Julius Popp; Ruth Schmid; Marc A Wollmer
Journal:  Praxis (Bern 1994)       Date:  2014-01-29

Review 5.  Sleep and Alzheimer disease pathology--a bidirectional relationship.

Authors:  Yo-El S Ju; Brendan P Lucey; David M Holtzman
Journal:  Nat Rev Neurol       Date:  2013-12-24       Impact factor: 42.937

6.  [Chloral hydrate: a hypnotic best forgotten?].

Authors:  J Gauillard; S Cheref; M N Vacherontrystram; J C Martin
Journal:  Encephale       Date:  2002 May-Jun       Impact factor: 1.291

7.  The effect of donepezil on sleep and REM sleep EEG in patients with Alzheimer disease: a double-blind placebo-controlled study.

Authors:  Walterandré dos Santos Moraes; Dalva Rollemberg Poyares; Christian Guilleminault; Luiz Roberto Ramos; Paulo Henrique Ferreira Bertolucci; Sergio Tufik
Journal:  Sleep       Date:  2006-02       Impact factor: 5.849

Review 8.  A systematic review of valerian as a sleep aid: safe but not effective.

Authors:  Diana M Taibi; Carol A Landis; Heidi Petry; Michael V Vitiello
Journal:  Sleep Med Rev       Date:  2007-06       Impact factor: 11.609

9.  Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease.

Authors:  Philip R Gehrman; Donald J Connor; Jennifer L Martin; Tamar Shochat; Jody Corey-Bloom; Sonia Ancoli-Israel
Journal:  Am J Geriatr Psychiatry       Date:  2009-02       Impact factor: 4.105

Review 10.  Sleep and neurodegenerative diseases.

Authors:  Sudhansu Chokroverty
Journal:  Semin Neurol       Date:  2009-09-09       Impact factor: 3.420

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  1 in total

Review 1.  [Treatment with psychotropic agents in patients with dementia and delirium : Gap between guideline recommendations and treatment practice].

Authors:  Walter Hewer; Christine Thomas
Journal:  Z Gerontol Geriatr       Date:  2017-01-25       Impact factor: 1.281

  1 in total

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