| Literature DB >> 25956806 |
Hayk A Harutyunyan1, Gohar V Sahakyan2.
Abstract
UNLABELLED: The aim of this study was to determine activities of pro-/antioxidant enzymes, reactive oxygen species (ROS) content, and oxidative modification of proteins and lipids in red blood cells (RBCs) and blood plasma of rats exposed to electrostatic field (200 kV/m) during the short (1 h) and the long periods (6 day, 6 h daily). Short-term exposure was characterized by the increase of oxidatively damaged proteins in blood of rats. This was strongly expressed in RBC membranes. After long-term action, RBC content in peripheral blood was higher than in control (P < 0.01) and the attenuation of prooxidant processes was shown. HIGHLIGHTS: External electrostatic field (200 kV/m) alters the balance in pro-/antioxidant processes. We examine oxidative processes in plasma and RBC (hemolysate and membranes). Biological effects of static electric field depend on exposure time. Acute action of electrostatic field (ESF) characterized by activation of the prooxidant processes. Long-term exposure reflected with prevalence of antioxidant activities.Entities:
Keywords: Carbonylation of proteins; Electrostatic field; Oxidative processes; Reactive oxygen species; Red blood cells
Mesh：
Substances：
Year: 2015 PMID： 25956806 DOI： 10.1007/s00484-015-1008-8
Source DB: PubMed Journal: Int J Biometeorol ISSN： 0020-7128 Impact factor: 3.787