Keiko Tanaka1, Shinichi Hitsumoto2, Yoshihiro Miyake3, Hitomi Okubo4, Satoshi Sasaki5, Nobuyuki Miyatake6, Masashi Arakawa7. 1. Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan. Electronic address: tanaka.keiko.jn@ehime-u.ac.jp. 2. Total Medical Support Center, Ehime University Hospital, Toon, Japan. 3. Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan. 4. Department of Health Promotion, National Institute of Public Health, Saitama, Japan. 5. Department of Social and Preventive Epidemiology, School of Public Health, The University of Tokyo, Tokyo, Japan. 6. Department of Hygiene, Faculty of Medicine, Kagawa University, Miki, Japan. 7. Health Tourism Research Center, Graduate School of Tourism Sciences, University of the Ryukyus, Okinawa, Japan.
Abstract
PURPOSE: The intrauterine environment, including maternal nutrition status, may affect the development, formation, and mineralization of children's teeth. We assessed the relationship between self-reported maternal dietary vitamin D intake during pregnancy and the risk of dental caries among young Japanese children. METHODS: This study is based on a prospective analysis of 1210 Japanese mother-child pairs. Information on maternal intake during pregnancy was collected using a validated diet history questionnaire. Data on oral examination at 36-46 months of age were obtained from the mothers, who transcribed the information from their maternal and child health handbooks to our self-administered questionnaire. Children were classified as having dental caries if one or more primary teeth had decayed or had been filled. RESULTS: Compared with the lowest quartile of maternal vitamin D intake during pregnancy, adjusted odds ratios (95% confidence intervals) for quartiles 2, 3, and 4 were 1.06 (0.72-1.56), 0.53 (0.34-0.81), and 0.67 (0.44-1.02), respectively (P for trend = .01). When maternal vitamin D intake was treated as a continuous variable, the adjusted odds ratio (95% confidence interval) was 0.94 (0.89-0.995). CONCLUSIONS: Higher maternal vitamin D intake during pregnancy may be associated with a lower risk of dental caries in children.
PURPOSE: The intrauterine environment, including maternal nutrition status, may affect the development, formation, and mineralization of children's teeth. We assessed the relationship between self-reported maternal dietary vitamin D intake during pregnancy and the risk of dental caries among young Japanese children. METHODS: This study is based on a prospective analysis of 1210 Japanese mother-child pairs. Information on maternal intake during pregnancy was collected using a validated diet history questionnaire. Data on oral examination at 36-46 months of age were obtained from the mothers, who transcribed the information from their maternal and child health handbooks to our self-administered questionnaire. Children were classified as having dental caries if one or more primary teeth had decayed or had been filled. RESULTS: Compared with the lowest quartile of maternal vitamin D intake during pregnancy, adjusted odds ratios (95% confidence intervals) for quartiles 2, 3, and 4 were 1.06 (0.72-1.56), 0.53 (0.34-0.81), and 0.67 (0.44-1.02), respectively (P for trend = .01). When maternal vitamin D intake was treated as a continuous variable, the adjusted odds ratio (95% confidence interval) was 0.94 (0.89-0.995). CONCLUSIONS: Higher maternal vitamin D intake during pregnancy may be associated with a lower risk of dental caries in children.
Authors: Justin T van der Tas; Marlies E C Elfrink; Annemieke C Heijboer; Fernando Rivadeneira; Vincent W V Jaddoe; Henning Tiemeier; Josje D Schoufour; Henriëtte A Moll; Edwin M Ongkosuwito; Eppo B Wolvius; Trudy Voortman Journal: Community Dent Oral Epidemiol Date: 2018-03-01 Impact factor: 3.383