Correction: Determining disease intervention strategies using spatially resolved simulations.

The image for Fig 4C is incorrect. Please see the complete, corrected Fig 4 here.

Fig 4

Effector T cell and clinical disease dynamics given anti-CD3 intervention at day 4.

Various efficacies of anti-CD3 intervention have been administered at day 4, which corresponds with encephalitogenic T cell priming. (A) Median effector T cell peak population sizes. (B) CD4Th1 population sizes at 40 days post-induction of EAE; red and blue bars indicate large and non-large effect magnitude changes with respect to the control group, in black. (C) Proportion of simulations that reach a particular maximum clinical disease score. A-test effect magnitude levels are given: 1, 2 and 3 *'s represent small, medium and large effects respectively. (D & E) Proportion of simulations contracting particular clinical scores or greater over time, for control (D) and a drug efficacy of 80% (E).