| Literature DB >> 25955488 |
Kristina Svennerholm, Michael Haney, Björn Biber, Erik Ulfhammer, Ott Saluveer, Pia Larsson, Elmir Omerovic, Sverker Jern, Niklas Bergh.
Abstract
Entities:
Year: 2015 PMID: 25955488 PMCID: PMC4425699 DOI: 10.1371/journal.pone.0128283
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 3Exhaustion in cumulative t-PA release.
In Panel A, the Control-1 (filled diamond, n = 16) and Control-2 (open diamond, n = 15) measurements show a pattern of exhaustion during the second stimulated t-PA release, starting early and continued throughout the sequence. Panel B shows the VPA treated group, with VPA-1 (filled square, n = 15) and VPA-2 (open square, n = 15) observations compared. There is no decrease observed in the second measurement until after 18 minutes. Panel C demonstrates a percent of the second measurement sequence compared to the first for both Control (filled triangles) and VPA (open triangles) (n = 13, where data was available for all measurements, treated and non-treated for the first and second sequences on both days). Minute 3 ratios reflect relatively small cumulative sums, possibly explaining the larger variation in the groups in Panel C. Data are presented as mean with 95% confidence intervals. * indicates p value less than 0.05 using repeated paired t tests.