Literature DB >> 25955239

Combination therapy of traditional Chinese medicine and Western medicine to treat refractory polymyositis: a case report.

Yu-Chen Cheng1, Ming-Yen Tsai, Chung-Jen Chen, Yu-Chiang Hung.   

Abstract

OBJECTIVE: To illustrate the potential for clinical improvement and regimen decrement in treating a patient with a refractory case of polymyositis (PM) with a combination of Western medicine and traditional Chinese medicine (TCM). INTERVENTIONS AND OUTCOME MEASURES: A 40-year-old man diagnosed with steroid-resistant PM in January 2011 demonstrated a poor response to immunosuppressants. Complementary TCM treatments were applied to treat his weakness at a clinic integrating TCM and rheumatology in February 2012. He was treated with herbal formula powders named "Bu-Zhong-Yi-Qi-Tang" and "Si-Jun-Zi-Tan." Within 1 month of treatment, the patient seemed to show significant improvement in the grade of disability. Daily doses of methotrexate and methylprednisolone were tapered to 25% and 95.8% after TCM treatments, respectively. Creatine phosphokinase also decreased from 6655 to 718 U/L until December 2013.
CONCLUSIONS: In our experience, weakness related to PM can be improved by invigorating the spleen-Qi with TCM treatments. This might indicate that TCM treatments can not only play a role in symptom control but also accelerate steroid tapping for refractory cases. Long-term follow-up and future experimental studies are warranted to examine the efficacy and explore the mechanism of TCM treatments for PM.

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Year:  2015        PMID: 25955239     DOI: 10.1089/acm.2014.0145

Source DB:  PubMed          Journal:  J Altern Complement Med        ISSN: 1075-5535            Impact factor:   2.579


  1 in total

Review 1.  Anticancer drug discovery from Chinese medicinal herbs.

Authors:  Mu-Yang Huang; Le-Le Zhang; Jian Ding; Jin-Jian Lu
Journal:  Chin Med       Date:  2018-07-04       Impact factor: 5.455

  1 in total

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