Literature DB >> 25954705

Comparative Evalution of G bone (Hydroxyapatite) and G-Graft (Hydroxyapatite with Collagen) as Bone Graft Material in Mandibular III Molar Extraction Socket.

Vijayendra Panday1, Vivekananda Upadhyaya2, Vikas Berwal3, Kapil Jain4, Nupur Sah5, Partha Sarathi6, Pushp Chander Swami7.   

Abstract

BACKGROUND: Bone grafting is a dynamic phenomenon. It is a surgical procedure that replaces missing bone with material either from patient's own body, or, an artificial, synthetic or natural substitute. A successful bone graft when applied, heals, becomes incorporated, re-vascularises and eventually assumes the form desired. AIMS AND
OBJECTIVE: The main purpose of this present study was to radiologically assess and compare the regenerative potential of hydroxyapatite with Collagen (G-Graft) and hydroxyapatite (G-Bone) and to evaluate the clinical usefulness of these materials to enhance bone healing in third molar extraction sites through bone formation.
MATERIALS AND METHODS: The study was carried out in the Department of Oral & Maxillofacilal Surgery, patients were divided into three groups. The rationale for assigning the patients to the groups was strictly random: Group I - G-Graft (Hydroxyapatite with Collagen) was used as Bone graft material, Group II - Bone graft material used was G-Bone (Hydroxyapatite), Group III-control group (no grafts was used). Orthopentomogram(OPG) images were taken intra-operatively, just after extraction in the Group III (control), after extraction but before graft placement in Group I & II (study groups) and post-operatively at the end of first month and third month. Bone density of the post-extraction sockets was measured at four random areas through 'densitometric analysis' software in the OPG program (Kodak 8000C Digital Panoramic System, Eastman Kodak Company) and an average value was recorded at each review.
RESULTS: The percentage increase in bone density between 1(st) month &amp; 3(rd) month was 7.55± 12.43 in Group I (G Graft), 4.41± 5.4859 in Group II (G Bone), while that Group III (control) was found to be -0.82 ± 3.96. The bone density increase was found to be statistically highly significant (p<0.01)) between all groups.
CONCLUSION: The present study concluded that G-Graft has a definite regenerative potential and is better than G-bone and can be used in bony defects to enhance the bone healing without provoking any significant inflammatory process. The study also indicates that defects treated with G-Graft attain more density initially and that G-Graft enhances bone healing in early stage.

Entities:  

Keywords:  Bone regeneration; Crystalline; Densitometric software

Year:  2015        PMID: 25954705      PMCID: PMC4413155          DOI: 10.7860/JCDR/2015/12140.5713

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  12 in total

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Review 2.  Principles of bone healing.

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Journal:  Neurosurg Focus       Date:  2001-04-15       Impact factor: 4.047

Review 3.  Collagen-hydroxyapatite composites for hard tissue repair.

Authors:  D A Wahl; J T Czernuszka
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6.  Application of rhBMP-7 and platelet-rich plasma in the treatment of long bone non-unions: a prospective randomised clinical study on 120 patients.

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8.  Autologous bone graft versus demineralized bone matrix in internal fixation of ununited long bones.

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Review 9.  Bone regenerative medicine: classic options, novel strategies, and future directions.

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10.  Biological assessment of a calcium silicate incorporated hydroxyapatite-gelatin nanocomposite: a comparison to decellularized bone matrix.

Authors:  Dong Joon Lee; Ricardo Padilla; He Zhang; Wei-Shou Hu; Ching-Chang Ko
Journal:  Biomed Res Int       Date:  2014-06-26       Impact factor: 3.411

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3.  Clinical and Radiographic Comparative Evaluation of Buccal and Palatal Corticotomy with Buccal Corticotomy in Periodontally Accelerated Osteogenic Orthodontics with Surgical Bur.

Authors:  Pavankumar Addanki; Jagadish Reddy Gooty; Rajababu Palaparthy
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4.  Periodontally accelerated osteogenic orthodontics: Novel perio-ortho interrelationship.

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5.  Extracellular matrix containing nanocomposite bone graft in periodontal regeneration - A randomized controlled clinical and radiographic evaluation.

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6.  Efficacy of Bovine Hydroxyapatite and Collagen Along With Platelet-Rich Fibrin as a Scaffold and Human Chorion as a Membrane for Ridge Preservation: A Case-Control Study.

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7.  Comparative evaluation of platelet-rich fibrin, platelet-rich fibrin + 50 wt% nanohydroxyapatite, platelet-rich fibrin + 50 wt% dentin chips on odontoblastic differentiation - An in vitro study-part 2.

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