Literature DB >> 25953706

Interaction effects in comorbid psychopathology.

Jared W Keeley1, Michael S Chmielewski2, R Michael Bagby3.   

Abstract

PURPOSE: Comorbidity in psychopathology is the norm. Despite some initial evidence, few studies have examined if the presence of comorbid conditions changes the expression of the pathology, either through increased severity of the syndrome(s) or by expanding to symptoms beyond the syndrome(s) (i.e., symptom overextension). The following report provides an illustration of interactive effects and overextension in comorbid pathology.
METHOD: A large pool of patients from a university hospital were assessed using SCID-I/P interviews. Of these, 230 patients diagnosed with major depressive disorder, social phobia, or both were included in the study.
RESULTS: Symptoms not belonging to either index condition (major depressive disorder or social phobia) reliably overextended in comorbid cases (odds ratios between 2.82 and 15.75).
CONCLUSIONS: Current research methodologies (e.g., structured interviews) do not allow for the examination of overextended symptoms. The authors make a call for future psychopathological research to search systematically for interactive effects by adopting more inclusive or flexible assessments.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2015        PMID: 25953706     DOI: 10.1016/j.comppsych.2015.04.008

Source DB:  PubMed          Journal:  Compr Psychiatry        ISSN: 0010-440X            Impact factor:   3.735


  2 in total

1.  Psychiatric disorders: natural kinds made by the world or practical kinds made by us?

Authors:  Peter Zachar
Journal:  World Psychiatry       Date:  2015-10       Impact factor: 49.548

2.  Use of Electronic Nicotine Delivery Systems among Adults with Mental Health Conditions, 2015.

Authors:  Claire Adams Spears; Dina M Jones; Scott R Weaver; Terry F Pechacek; Michael P Eriksen
Journal:  Int J Environ Res Public Health       Date:  2016-12-23       Impact factor: 3.390

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.