Literature DB >> 2595307

Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats.

S Ueda1, T Yoshikawa, S Takahashi, H Ichikawa, M Yasuda, H Oyamada, T Tanigawa, S Sugino, M Kondo.   

Abstract

Ischemia and reperfusion are of the greatest importance in the pathology of many diseases. We investigated the roles of oxygen-derived free radicals and lipid peroxidation in gastric mucosal injury, such as spotty and linear hemorrhagic erosions, induced in rats by ischemia-reperfusion. The gastric mucosal injury and the increase in thiobarbituric acid (TBA) reactants in the gastric mucosa induced by ischemia-reperfusion were significantly inhibited by treatment with SOD and catalase. These results suggest that oxygen-derived free radicals and lipid peroxidation play important roles in the pathogenesis of acute gastric mucosal lesions induced by ischemia-reperfusion.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2595307     DOI： 10.3109/00365528909091124

Source DB:  PubMed          Journal:  Scand J Gastroenterol Suppl        ISSN： 0085-5928


  7 in total

1.  Geraniol-a flavoring agent with multifunctional effects in protecting the gastric and duodenal mucosa.

Authors:  Katharinne Ingrid Moraes de Carvalho; Flavia Bonamin; Raquel Cássia Dos Santos; Larissa Lucena Périco; Fernando Pereira Beserra; Damião Pergentino de Sousa; José Maria Barbosa Filho; Lucia Regina Machado da Rocha; Clelia Akiko Hiruma-Lima
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2013-12-17       Impact factor: 3.000

2.  Gastroprotective mechanisms of the chloroform and ethyl acetate phases of Praxelis clematidea (Griseb.) R.M.King & H.Robinson (Asteraceae).

Authors:  Heloina de Sousa Falcão; Gabriela Lemos de Azevedo Maia; Flávia Bonamin; Hélio Kushima; Thiago Mello Moraes; Clélia Akiko Hiruma Lima; Christiane Takayama; Anderson Luiz Ferreira; Alba Regina Monteiro Souza Brito; Maria de Fátima Agra; José Maria Barbosa Filho; Leônia Maria Batista
Journal:  J Nat Med       Date:  2012-09-15       Impact factor: 2.343

3.  Sequence of gastric mucosal injury following ischemia and reperfusion. Role of reactive oxygen metabolites.

Authors:  F J Andrews; C Malcontenti; P E O'Brien
Journal:  Dig Dis Sci       Date:  1992-09       Impact factor: 3.199

4.  Antioxidant action of mangrove polyphenols against gastric damage induced by absolute ethanol and ischemia-reperfusion in the rat.

Authors:  Felipe Meira de-Faria; Ana Cristina Alves Almeida; Anderson Luiz-Ferreira; Christiane Takayama; Ricardo José Dunder; Marcelo Aparecido da Silva; Marcos José Salvador; Patrícia Verardi Abdelnur; Marcos Nogueira Eberlin; Wagner Vilegas; Walber Toma; Alba Regina Monteiro Souza-Brito
Journal:  ScientificWorldJournal       Date:  2012-04-30

5.  Effects of Thymus hirtus sp. algeriensis Boiss. et Reut. (Lamiaceae) essential oil on healing gastric ulcers according to sex.

Authors:  Fatma Guesmi; Manel Ben Ali; Taha Barkaoui; Wiem Tahri; Mondher Mejri; Mossadok Ben-Attia; Houda Bellamine; Ahmed Landoulsi
Journal:  Lipids Health Dis       Date:  2014-08-26       Impact factor: 3.876

6.  Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus.

Authors:  Leônia Maria Batista; Gedson Rodrigues De Morais Lima; Ana Beatriz Albino De Almeida; Luciana De Pietro Magri; Tamara Regina Calvo; Anderson Luiz Ferreira; Cláudia Helena Pellizzon; Clélia Akiko Hiruma-Lima; Wagner Vilegas; Paulo Takeo Sano; Alba Regina Monteiro Souza Brito
Journal:  BMC Complement Altern Med       Date:  2015-10-29       Impact factor: 3.659

7.  Healing, antioxidant and cytoprotective properties of Indigofera truxillensis in different models of gastric ulcer in rats.

Authors:  Anderson Luiz-Ferreira; Maira Cola; Victor Barbastefano; Felipe Meira de-Faria; Ana Beatriz A de Almeida; Elisângela Farias-Silva; Tamara Regina Calvo; Clélia A Hiruma-Lima; Wagner Vilegas; Alba Regina M Souza-Brito
Journal:  Int J Mol Sci       Date:  2012-11-15       Impact factor: 5.923
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.