| Literature DB >> 25952114 |
Hui Qin1, Huiliang Cao2, Yaochao Zhao1, Guodong Jin2, Mengqi Cheng1, Jiaxin Wang1, Yao Jiang1, Zhiquan An1, Xianlong Zhang1, Xuanyong Liu2.
Abstract
Prevention of implant loosening and infection is crucial to orthopedic and dental surgeries. In this work, the surface of stainless steel (SS) was modified by silver-sourced plasma immersion ion implantation (Ag-PIII). Metallic silver nanoparticles with various diameters and distributions were fabricated on the SS surfaces after treatment with Ag-PIII for 0.5 and 1.5 h, respectively. The osteogenic activity and antimicrobial properties of SS before and after Ag-PIII treatment were evaluated using in vitro and in vivo tests. The results demonstrated that Ag-PIII treatment not only promoted the antibacterial activity of SS but also enhanced the osteogenic differentiation of human bone marrow stromal cells.Entities:
Keywords: antimicrobial; osteogenic; plasma immersion ion implantation; silver; stainless steel
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Year: 2015 PMID： 25952114 DOI： 10.1021/acsami.5b01310
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN： 1944-8244 Impact factor: 9.229