Mun-Kun Hong1, Ming-Hsun Lee2, Dah-Ching Ding3, Sung-Chao Chu4, Tang-Yuan Chu5. 1. Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Graduate Institute of Medical Science, Tzu Chi University, Hualien, Taiwan. 2. Department of Pathology, Buddhist Tzu Chi General Hospital and University, Hualien, Taiwan. 3. Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan. 4. Department of Hematology-Oncology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan. 5. Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Graduate Institute of Medical Science, Tzu Chi University, Hualien, Taiwan. Electronic address: hidrchu@gmail.com.
Abstract
OBJECTIVE: This report describes a case of serous ovarian carcinoma with occult serous tubal intraepithelial carcinoma (STIC), which presented as atypical glandular cells favor neoplasia (AGC-FN) with Pap cytology and dermatomyositis. CASE REPORT: A 48-year-old woman presented with symptoms of dermatomyositis. An AGC-FN result from a Pap smear, with an absence of a cervical or endometrial lesion was noted. After cancer surveillance, ovarian high grade serous carcinoma associated with serous tubal intraepithelial carcinoma was diagnosed. Two weeks following surgical excision of the carcinoma, dramatic remission of the dermatomyositis symptoms was evident. CONCLUSION: The patient had serous carcinoma of the ovary with tubal STIC, which presented as dermatomyositis. The AGC-FN identified from a Pap smear hinted at a diagnosis of ovarian carcinoma. These presentations point to an occult malignancy in the genital tract and demand careful diagnostic workup.
OBJECTIVE: This report describes a case of serous ovarian carcinoma with occult serous tubal intraepithelial carcinoma (STIC), which presented as atypical glandular cells favor neoplasia (AGC-FN) with Pap cytology and dermatomyositis. CASE REPORT: A 48-year-old woman presented with symptoms of dermatomyositis. An AGC-FN result from a Pap smear, with an absence of a cervical or endometrial lesion was noted. After cancer surveillance, ovarian high grade serous carcinoma associated with serous tubal intraepithelial carcinoma was diagnosed. Two weeks following surgical excision of the carcinoma, dramatic remission of the dermatomyositis symptoms was evident. CONCLUSION: The patient had serous carcinoma of the ovary with tubal STIC, which presented as dermatomyositis. The AGC-FN identified from a Pap smear hinted at a diagnosis of ovarian carcinoma. These presentations point to an occult malignancy in the genital tract and demand careful diagnostic workup.