Dan Mihu1, Ciortea Razvan1, Andrei Malutan2, Carmen Mihaela3. 1. 2nd Department of Obstetrics and Gynecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012, Cluj-Napoca, Romania. 2. 2nd Department of Obstetrics and Gynecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012, Cluj-Napoca, Romania. Electronic address: malutan.andrei@gmail.com. 3. Department of Histology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012, Cluj-Napoca, Romania.
Abstract
OBJECTIVE: To evaluate the systemic inflammatory response in preeclampsia compared to normal pregnancy. MATERIALS AND METHODS: The following serum parameters were determined in three groups of patients: leukocytes, neutrophils, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), and certain markers of oxidative stress. Fetal status was assessed based on the gestational age at which birth occurred, on the Apgar score, and on fetal weight. RESULTS: In preeclampsia, a higher systemic inflammatory status was found compared to normal pregnancy. Gestational age at birth, fetal weight, and Apgar score were significantly lower in the group with preeclampsia compared to normal pregnancy. CONCLUSION: In preeclampsia, there is an increased systemic inflammatory response compared to normal pregnancy, which can influence fetal status at birth.
OBJECTIVE: To evaluate the systemic inflammatory response in preeclampsia compared to normal pregnancy. MATERIALS AND METHODS: The following serum parameters were determined in three groups of patients: leukocytes, neutrophils, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), and certain markers of oxidative stress. Fetal status was assessed based on the gestational age at which birth occurred, on the Apgar score, and on fetal weight. RESULTS: In preeclampsia, a higher systemic inflammatory status was found compared to normal pregnancy. Gestational age at birth, fetal weight, and Apgar score were significantly lower in the group with preeclampsia compared to normal pregnancy. CONCLUSION: In preeclampsia, there is an increased systemic inflammatory response compared to normal pregnancy, which can influence fetal status at birth.
Authors: Priscila R Nunes; Mariana Romão-Veiga; José C Peraçoli; Roberto A Araujo Costa; Leandro G de Oliveira; Vera Therezinha M Borges; Maria Terezinha Peraçoli Journal: Immunol Res Date: 2019-06 Impact factor: 2.829
Authors: Alejandro Majali-Martinez; Philipp Velicky; Jürgen Pollheimer; Martin Knöfler; Hong Wa Yung; Graham J Burton; Nassim Ghaffari Tabrizi-Wizsy; Uwe Lang; Ursula Hiden; Gernot Desoye; Martina Dieber-Rotheneder Journal: Hum Reprod Date: 2016-11-17 Impact factor: 6.918