Literature DB >> 25949898

Targeting tumor-associated myeloid cells for cancer immunotherapy.

Hong Qin1, Guowei Wei1, Dongho Gwak1, Zhenyuan Dong1, Ailian Xiong1, Larry W Kwak1.   

Abstract

Tumor-associated myeloid cells undermine the therapeutic efficacy of cancer immunotherapy by their inhibitory properties on immune effector cells. Development of therapeutic agents to deplete suppressive myeloid cells in tumor microenvironment requires identification of cell-specific targets. A competitive phage display technique on live cells paves the way to discovery of such a target.

Entities:  

Keywords:  immunosuppression; immunotherapy; myeloid-derived suppressor cells; peptibody; tumor microenvironment

Year:  2015        PMID： 25949898      PMCID： PMC4404802          DOI： 10.4161/2162402X.2014.983761

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

1.  Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma.

Authors:  Stephen J Schuster; Sattva S Neelapu; Barry L Gause; John E Janik; Franco M Muggia; Jon P Gockerman; Jane N Winter; Christopher R Flowers; Daniel A Nikcevich; Eduardo M Sotomayor; Dean S McGaughey; Elaine S Jaffe; Elise A Chong; Craig W Reynolds; Donald A Berry; Carlos F Santos; Mihaela A Popa; Amy M McCord; Larry W Kwak
Journal:  J Clin Oncol       Date:  2011-05-31       Impact factor: 44.544

2.  S100A9 a new marker for monocytic human myeloid-derived suppressor cells.

Authors:  Fei Zhao; Bastian Hoechst; Austin Duffy; Jaba Gamrekelashvili; Suzanne Fioravanti; Michael P Manns; Tim F Greten; Firouzeh Korangy
Journal:  Immunology       Date:  2012-06       Impact factor: 7.397

Review 3.  Myeloid-derived suppressor cell heterogeneity and subset definition.

Authors:  Elisa Peranzoni; Serena Zilio; Ilaria Marigo; Luigi Dolcetti; Paola Zanovello; Susanna Mandruzzato; Vincenzo Bronte
Journal:  Curr Opin Immunol       Date:  2010-02-17       Impact factor: 7.486

4.  Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma.

Authors:  M Bendandi; C D Gocke; C B Kobrin; F A Benko; L A Sternas; R Pennington; T M Watson; C W Reynolds; B L Gause; P L Duffey; E S Jaffe; S P Creekmore; D L Longo; L W Kwak
Journal:  Nat Med       Date:  1999-10       Impact factor: 53.440

5.  Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine.

Authors:  Paola Filipazzi; Roberta Valenti; Veronica Huber; Lorenzo Pilla; Paola Canese; Manuela Iero; Chiara Castelli; Luigi Mariani; Giorgio Parmiani; Licia Rivoltini
Journal:  J Clin Oncol       Date:  2007-06-20       Impact factor: 44.544

6.  Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humans.

Authors:  Güllü Topal Görgün; Gregory Whitehill; Jennifer L Anderson; Teru Hideshima; Craig Maguire; Jacob Laubach; Noopur Raje; Nikhil C Munshi; Paul G Richardson; Kenneth C Anderson
Journal:  Blood       Date:  2013-01-15       Impact factor: 22.113

7.  Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells.

Authors:  KiBem Kim; Andrew D Skora; Zhaobo Li; Qiang Liu; Ada J Tam; Richard L Blosser; Luis A Diaz; Nickolas Papadopoulos; Kenneth W Kinzler; Bert Vogelstein; Shibin Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2014-07-28       Impact factor: 11.205

Review 8.  Myeloid-derived suppressor cells as regulators of the immune system.

Authors:  Dmitry I Gabrilovich; Srinivas Nagaraj
Journal:  Nat Rev Immunol       Date:  2009-03       Impact factor: 53.106

9.  Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells.

Authors:  Sandeep S Dave; George Wright; Bruce Tan; Andreas Rosenwald; Randy D Gascoyne; Wing C Chan; Richard I Fisher; Rita M Braziel; Lisa M Rimsza; Thomas M Grogan; Thomas P Miller; Michael LeBlanc; Timothy C Greiner; Dennis D Weisenburger; James C Lynch; Julie Vose; James O Armitage; Erlend B Smeland; Stein Kvaloy; Harald Holte; Jan Delabie; Joseph M Connors; Peter M Lansdorp; Qin Ouyang; T Andrew Lister; Andrew J Davies; Andrew J Norton; H Konrad Muller-Hermelink; German Ott; Elias Campo; Emilio Montserrat; Wyndham H Wilson; Elaine S Jaffe; Richard Simon; Liming Yang; John Powell; Hong Zhao; Neta Goldschmidt; Michael Chiorazzi; Louis M Staudt
Journal:  N Engl J Med       Date:  2004-11-18       Impact factor: 91.245

10.  Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice.

Authors:  Hong Qin; Beatrisa Lerman; Ippei Sakamaki; Guowei Wei; Soungchul C Cha; Sheetal S Rao; Jianfei Qian; Yared Hailemichael; Roza Nurieva; Karen C Dwyer; Johannes Roth; Qing Yi; Willem W Overwijk; Larry W Kwak
Journal:  Nat Med       Date:  2014-05-25       Impact factor: 53.440
  10 in total
  6 in total

1.  Targeting STAT3 signaling reduces immunosuppressive myeloid cells in head and neck squamous cell carcinoma.

Authors:  Lin-Lin Bu; Guang-Tao Yu; Wei-Wei Deng; Liang Mao; Jian-Feng Liu; Si-Rui Ma; Teng-Fei Fan; Bradford Hall; Ashok B Kulkarni; Wen-Feng Zhang; Zhi-Jun Sun
Journal:  Oncoimmunology       Date:  2016-01-19       Impact factor: 8.110

2.  CD24 blunts oral squamous cancer development and dampens the functional expansion of myeloid-derived suppressor cells.

Authors:  Caroline W Fugle; Yongliang Zhang; Feng Hong; Shaoli Sun; Caroline Westwater; Saleh Rachidi; Hong Yu; Elizabeth Garret-Mayer; Keith Kirkwood; Bei Liu; Zihai Li
Journal:  Oncoimmunology       Date:  2016-09-26       Impact factor: 8.110

3.  Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma.

Authors:  Peng Zhang; Jason Miska; Catalina Lee-Chang; Aida Rashidi; Wojciech K Panek; Shejuan An; Markella Zannikou; Aurora Lopez-Rosas; Yu Han; Ting Xiao; Katarzyna C Pituch; Deepak Kanojia; Irina V Balyasnikova; Maciej S Lesniak
Journal:  Proc Natl Acad Sci U S A       Date:  2019-11-11       Impact factor: 11.205

4.  Impact of myeloid-derived suppressor cell on Kupffer cells from mouse livers with hepatocellular carcinoma.

Authors:  Stéphanie Lacotte; Florence Slits; Lorenzo A Orci; Jeremy Meyer; Graziano Oldani; Vaihere Delaune; Carmen Gonelle-Gispert; Philippe Morel; Christian Toso
Journal:  Oncoimmunology       Date:  2016-09-20       Impact factor: 8.110

Review 5.  Translational Potential of Therapeutics Targeting Regulatory Myeloid Cells in Tuberculosis.

Authors:  Nelita du Plessis; Leigh A Kotze; Vinzeigh Leukes; Gerhard Walzl
Journal:  Front Cell Infect Microbiol       Date:  2018-09-21       Impact factor: 5.293

Review 6.  Local Delivery and Glioblastoma: Why Not Combining Sustained Release and Targeting?

Authors:  Claire Gazaille; Marion Sicot; Patrick Saulnier; Joël Eyer; Guillaume Bastiat
Journal:  Front Med Technol       Date:  2021-11-22
  6 in total

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