Anggoro B Hartopo1, Ira Puspitawati, Budi Y Setianto. 1. Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Gadjah Mada - Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Abstract
AIM: to investigate the role of neutrophil-to-lymphocyte ratio (NLratio) in predicting in-hospital adverse cardiac events in patients with STEMI. METHODS: this was a cohort study on patients with STEMI onset 24 hour hospitalised in ICCU. NLratio was calculated as absolute neutrophil count divided with lymphocyte count measured by automated blood cell counter on admission.The outcome was in-hospital adverse cardiac events, which were recorded during follow-up. The cut-off value of NLratio to predict outcome was determined by ROC curve analysis. Univariate and multivariable analysis to assess whether high NLratio was independent predictor for in-hospital adverse events were performed. RESULTS: among 165 subjects, in-hospital adverse cardiac events occurred in 49 subjects (29%). The cut-off value of NLratio was 6.2. The univariate analysis showed that NLratio >6.2 had an odd ratio of 3.19 (95% CI 1.55-6.55, p=0.002) to develop in-hospital adverse cardiac events. The multivariate analysis showed that NLratio was an independent predictor of in-hospital adverse cardiac events with an odd ratio of 4.10 (95% CI 1.59-10.54, p=0.003). CONCLUSION: high on-admission NLratio is an independent predictor for in-hospital adverse cardiac events in patients hospitalised for STEMI.
AIM: to investigate the role of neutrophil-to-lymphocyte ratio (NLratio) in predicting in-hospital adverse cardiac events in patients with STEMI. METHODS: this was a cohort study on patients with STEMI onset 24 hour hospitalised in ICCU. NLratio was calculated as absolute neutrophil count divided with lymphocyte count measured by automated blood cell counter on admission.The outcome was in-hospital adverse cardiac events, which were recorded during follow-up. The cut-off value of NLratio to predict outcome was determined by ROC curve analysis. Univariate and multivariable analysis to assess whether high NLratio was independent predictor for in-hospital adverse events were performed. RESULTS: among 165 subjects, in-hospital adverse cardiac events occurred in 49 subjects (29%). The cut-off value of NLratio was 6.2. The univariate analysis showed that NLratio >6.2 had an odd ratio of 3.19 (95% CI 1.55-6.55, p=0.002) to develop in-hospital adverse cardiac events. The multivariate analysis showed that NLratio was an independent predictor of in-hospital adverse cardiac events with an odd ratio of 4.10 (95% CI 1.59-10.54, p=0.003). CONCLUSION: high on-admission NLratio is an independent predictor for in-hospital adverse cardiac events in patients hospitalised for STEMI.
Authors: José Gildo de Moura Monteiro Júnior; Dilênia de Oliveira Cipriano Torres; Maria Cleide Freire Clementino da Silva; Cyntia Maria de Holanda Martins; Izadora Karina da Silva; Monique Evelyn Mendonça do Nascimento; Ana Célia Oliveira Dos Santos; Ulisses Ramos Montarroyos; Dário Celestino Sobral Filho Journal: PLoS One Date: 2018-04-18 Impact factor: 3.240
Authors: Ahmet Zengin; Mehmet Karaca; Emre Aruğaslan; Ersin Yıldırım; Mehmet Baran Karataş; Yiğit Çanga; Ayşe Emre; Gülşah Tayyareci Journal: J Cardiovasc Thorac Res Date: 2021-03-01