Antonio Augusto Santos Paulo1,2, Maria Helena Ruivo Solheiro3, Carolina Oliveira Santos Paulo4. 1. Department of Obstetrics and Gynecology, Hospital Centre Tondela-Viseu, Avda. Rei D.Duarte, 3504-509, Viseu, Portugal. antoniosantospaulo@sapo.pt. 2. Health Sciences Department, University of Aveiro, Aveiro, Portugal. antoniosantospaulo@sapo.pt. 3. Department of Obstetrics and Gynecology, Hospital Centre Tondela-Viseu, Avda. Rei D.Duarte, 3504-509, Viseu, Portugal. 4. Farmacia Avenida, Mangualde, Portugal.
Abstract
BACKGROUND: Hysteroscopy is an indispensable approach in gynecology. Miniaturization may reduce pain allowing office procedures without anesthesia. OBJECTIVES: Our main objective is to determine if modifications in scope diameters have made office hysteroscopy less painful. SEARCH STRATEGY: Studies were sought with key words "hysteroscopy" and "pain" from available online sources. Time frame was from 2000 onward. Thirty-three articles were retrieved for detailed analysis. SELECTION CRITERIA: Prospective randomized trials, studying pain as main outcome in office hysteroscopy expressed in means, confidence intervals and SD, comparing office mini-hysteroscopy to conventional hysteroscopy. Studies or arms within a study where conscientious sedation, anesthesia or non-steroidal drugs were used were excluded. DATA COLLECTION AND ANALYSIS: We analyzed data from eight studies (seven RCT) comparing mini-hysteroscopy with conventional scopes, involving a total of twenty-three hundred and twenty-two participants, of which nineteen hundred and eighty-six completed the intervention. MAIN RESULTS: A meta-analysis revealed a significant reduction pain score (MD: -3.64; 95 % CI -5.16 to -2.12; test for overall effect p < 0.00001) and available data support miniaturization decreases pain in outpatient hysteroscopy. CONCLUSIONS: Pain in office hysteroscopy is lower with mini-hysteroscopes.
BACKGROUND: Hysteroscopy is an indispensable approach in gynecology. Miniaturization may reduce pain allowing office procedures without anesthesia. OBJECTIVES: Our main objective is to determine if modifications in scope diameters have made office hysteroscopy less painful. SEARCH STRATEGY: Studies were sought with key words "hysteroscopy" and "pain" from available online sources. Time frame was from 2000 onward. Thirty-three articles were retrieved for detailed analysis. SELECTION CRITERIA: Prospective randomized trials, studying pain as main outcome in office hysteroscopy expressed in means, confidence intervals and SD, comparing office mini-hysteroscopy to conventional hysteroscopy. Studies or arms within a study where conscientious sedation, anesthesia or non-steroidal drugs were used were excluded. DATA COLLECTION AND ANALYSIS: We analyzed data from eight studies (seven RCT) comparing mini-hysteroscopy with conventional scopes, involving a total of twenty-three hundred and twenty-two participants, of which nineteen hundred and eighty-six completed the intervention. MAIN RESULTS: A meta-analysis revealed a significant reduction pain score (MD: -3.64; 95 % CI -5.16 to -2.12; test for overall effect p < 0.00001) and available data support miniaturization decreases pain in outpatient hysteroscopy. CONCLUSIONS:Pain in office hysteroscopy is lower with mini-hysteroscopes.
Authors: Giovanni Buzzaccarini; Luis Alonso Pacheco; Amerigo Vitagliano; Sergio Haimovich; Vito Chiantera; Péter Török; Salvatore Giovanni Vitale; Antonio Simone Laganà; Jose Carugno Journal: Medicina (Kaunas) Date: 2022-08-20 Impact factor: 2.948
Authors: Mustafa Gazi; Süheyla Abitağaoğlu; Güldem Turan; Ceren Köksal; Fatma Nur Akgün; Dilek E Ari Journal: Saudi Med J Date: 2018-10 Impact factor: 1.484