Literature DB >> 25947042

Are we entering a new age for human vaccine adjuvants?

Derek T O'Hagan1, Christopher B Fox.   

Abstract

Major advances in adjuvant development for human vaccines have been reported recently for a range of indications, including malaria, influenza and varicella zoster virus. Furthermore, there is an increased understanding of adjuvant mechanisms of action and a greater emphasis on the importance of formulation and characterization. This progress may signify a new golden age of vaccine adjuvant discovery and development.

Entities:  

Keywords:  MF59; MPL; QS21; formulation; vaccine adjuvant

Mesh：

Substances：

Year:  2015        PMID： 25947042     DOI： 10.1586/14760584.2015.1043273

Source DB:  PubMed          Journal:  Expert Rev Vaccines        ISSN： 1476-0584            Impact factor:   5.217


  9 in total

1.  It is time to accelerate building local vaccine adjuvant manufacturing capacity.

Authors:  Christopher B Fox
Journal:  Ther Adv Vaccines Immunother       Date:  2017-10-09

2.  Accounting for adjuvant-induced artifacts in the characterization of vaccine formulations by polyacrylamide gel electrophoresis.

Authors:  Virginie Jakob; Livia Brunner; Christophe Barnier-Quer; Molly Blust; Nicolas Collin; Lauren Carter; Darrick Carter; Kelly M Rausch; Christopher B Fox
Journal:  Ther Adv Vaccines       Date:  2017-05-03

3.  A De-O-acylated Lipooligosaccharide-Based Adjuvant System Promotes Antibody and Th1-Type Immune Responses to H1N1 Pandemic Influenza Vaccine in Mice.

Authors:  Ji In Ryu; Shin Ae Park; Seo Ri Wui; Ara Ko; Ji Eun Han; Jung Ah Choi; Man Ki Song; Kwang Sung Kim; Yang Je Cho; Na Gyong Lee
Journal:  Biomed Res Int       Date:  2016-11-07       Impact factor: 3.411

4.  Brief exposure of skin to near-infrared laser augments early vaccine responses.

Authors:  Shinya Yokomizo; Wataru Katagiri; Yohei Maki; Tomoya Sano; Kazumasa Inoue; Masahiro Fukushi; Dmitriy N Atochin; Toshihiro Kushibiki; Akihiko Kawana; Yoshifumi Kimizuka; Satoshi Kashiwagi
Journal:  Nanophotonics       Date:  2021-08-09       Impact factor: 7.923

5.  Kinome Analysis to Define Mechanisms of Adjuvant Action: PCEP Induces Unique Signaling at the Injection Site and Lymph Nodes.

Authors:  Sunita Awate; Erin Scruten; George Mutwiri; Scott Napper
Journal:  Vaccines (Basel)       Date:  2022-06-11

6.  Starch-based NP act as antigen delivery systems without immunomodulating effect.

Authors:  François Fasquelle; Laurent Dubuquoy; Didier Betbeder
Journal:  PLoS One       Date:  2022-07-29       Impact factor: 3.752

7.  Modulation of Innate Immune Responses via Covalently Linked TLR Agonists.

Authors:  Janine K Tom; Emmanuel Y Dotsey; Hollie Y Wong; Lalisa Stutts; Troy Moore; D Huw Davies; Philip L Felgner; Aaron P Esser-Kahn
Journal:  ACS Cent Sci       Date:  2015-10-28       Impact factor: 14.553

8.  The influence of adjuvant on UreB protection against Helicobacter pylori through the diversity of CD4+ T-cell epitope repertoire.

Authors:  Bin Li; Hanmei Yuan; Li Chen; Heqiang Sun; Jian Hu; Shanshan Wei; Zhuo Zhao; Quanming Zou; Chao Wu
Journal:  Oncotarget       Date:  2017-07-12

Review 9.  Immunobiology of Carbohydrates: Implications for Novel Vaccine and Adjuvant Design Against Infectious Diseases.

Authors:  Giuseppe Stefanetti; Francesco Borriello; Barbara Richichi; Ivan Zanoni; Luigi Lay
Journal:  Front Cell Infect Microbiol       Date:  2022-01-18       Impact factor: 5.293
  9 in total

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