Literature DB >> 25946166

DhITACT: DNA Hydrogel Formation by Isothermal Amplification of Complementary Target in Fluidic Channels.

Ho Yeon Lee1, Hansaem Jeong1, Il Young Jung1, Bora Jang1, Young Chang Seo2, Haeshin Lee2, Hyukjin Lee1.   

Abstract

DNA hydrogel formation by isothermal amplification of complementary targets in microfluidic channels (DhITACT) is a new platform for rapid and accurate detection of infectious pathogens. DNA hydrogel is formed in situ within microfluidic channels by the isothermal rolling circle amplification process upon the selective binding of target strands from the biological fluid. Once the volume of DNA hydrogel sufficiently enlarges, it can selectively block the matching channels with target pathogens.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  DNA hydrogel; microfluidic array chip; molecular diagnostic platform; rolling circle amplification

Mesh：

Substances：

Year:  2015        PMID： 25946166     DOI： 10.1002/adma.201500414

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  7 in total

1.  Self-assembled DNA nanoclews for the efficient delivery of CRISPR-Cas9 for genome editing.

Authors:  Wujin Sun; Wenyan Ji; Jordan M Hall; Quanyin Hu; Chao Wang; Chase L Beisel; Zhen Gu
Journal:  Angew Chem Int Ed Engl       Date:  2015-08-27       Impact factor: 15.336

Review 2.  Microfluidic-based approaches for COVID-19 diagnosis.

Authors:  Hsuan-Yu Mu; Yu-Lun Lu; Tzu-Hung Hsiao; Jen-Huang Huang
Journal:  Biomicrofluidics       Date:  2020-12-08       Impact factor: 2.800

3.  An open-space microfluidic chip with fluid walls for online detection of VEGF via rolling circle amplification.

Authors:  Shuo Feng; Sifeng Mao; Jinxin Dou; Weiwei Li; Haifang Li; Jin-Ming Lin
Journal:  Chem Sci       Date:  2019-07-25       Impact factor: 9.825

4.  Rapid molecular diagnosis of infectious viruses in microfluidics using DNA hydrogel formation.

Authors:  Wonhwi Na; Dongwoo Nam; Hoyoon Lee; Sehyun Shin
Journal:  Biosens Bioelectron       Date:  2018-02-19       Impact factor: 10.618

Review 5.  DNA hydrogel-empowered biosensing.

Authors:  Sima Khajouei; Hadi Ravan; Ali Ebrahimi
Journal:  Adv Colloid Interface Sci       Date:  2019-10-31       Impact factor: 12.984

6.  A Lateral Flow Assay for Nucleic Acid Detection Based on Rolling Circle Amplification Using Capture Ligand-Modified Oligonucleotides.

Authors:  Ha Neul Lee; Juhee Lee; Yoo Kyung Kang; Joo Hoon Lee; Seungju Yang; Hyun Jung Chung
Journal:  Biochip J       Date:  2022-09-06       Impact factor: 4.229

Review 7.  Stimuli-responsive DNA-based hydrogels for biosensing applications.

Authors:  Mengmeng Chen; Yu Wang; Jingyang Zhang; Yuan Peng; Shuang Li; Dianpeng Han; Shuyue Ren; Kang Qin; Sen Li; Zhixian Gao
Journal:  J Nanobiotechnology       Date:  2022-01-21       Impact factor: 10.435
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.