Literature DB >> 25945946

AN OPEN TRIAL OF EMOTION REGULATION THERAPY FOR GENERALIZED ANXIETY DISORDER AND COOCCURRING DEPRESSION.

Douglas S Mennin1, David M Fresco2, Michael Ritter3, Richard G Heimberg4.   

Abstract

BACKGROUND: Although CBT is efficacious for a wide variety of psychiatric conditions, relatively fewer GAD patients achieve high endstate functioning as compared to patients receiving CBTs for other disorders. Moreover, GAD trials that utilized patient samples without prominent depression have tended to report that effect sizes for depressive outcomes were small or diminished to pretreatment levels in the follow-up period. Emotion regulation therapy (ERT) integrates principles from traditional and contemporary cognitive behavioral treatments with basic and translational findings from affect science to offer a blueprint for improving intervention by focusing on motivational, regulatory, and contextual learning mechanisms.
METHOD: The purpose of this investigation was to provide initial support for the efficacy of ERT in an open trial of patients with GAD and cooccurring depressive symptoms. Twenty-one patients received a 20-session version of ERT delivered in weekly individual sessions. Standardized clinician ratings and self-report measures were assessed at pre-, mid-, and posttreatment as well as at three- and nine-month follow-ups. Intent-to-treat analyzes were utilized.
RESULTS: GAD patients, half with comorbid major depression, evidenced statistically, and clinically meaningful improvements in symptom severity, impairment, quality of life, and in model-related outcomes including emotional/motivational intensity, mindful attending/acceptance, decentering, and cognitive reappraisal. Patients maintained gains across the three and nine month follow-up periods.
CONCLUSIONS: These findings, although preliminary, provide additional evidence for the role of emotion dysregulation in the onset, maintenance, and now treatment of conditions such as GAD and cooccurring depressive symptoms.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  anxiety/anxiety disorders; behavior therapy; clinical trials; depression; emotion regulation; generalized anxiety disorder; mindfulness/meditation; treatment

Mesh:

Year:  2015        PMID: 25945946      PMCID: PMC4515189          DOI: 10.1002/da.22377

Source DB:  PubMed          Journal:  Depress Anxiety        ISSN: 1091-4269            Impact factor:   6.505


  56 in total

1.  Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being.

Authors:  James J Gross; Oliver P John
Journal:  J Pers Soc Psychol       Date:  2003-08

Review 2.  Emotion dysregulation model of mood and anxiety disorders.

Authors:  Stefan G Hofmann; Alice T Sawyer; Angela Fang; Anu Asnaani
Journal:  Depress Anxiety       Date:  2012-03-16       Impact factor: 6.505

3.  The data of diagnosis: new approaches to psychiatric classification.

Authors:  Bruce Cuthbert; Thomas Insel
Journal:  Psychiatry       Date:  2010       Impact factor: 2.458

Review 4.  Emotion regulation: taking stock and moving forward.

Authors:  James J Gross
Journal:  Emotion       Date:  2013-03-25

5.  Preliminary evidence for an emotion dysregulation model of generalized anxiety disorder.

Authors:  Douglas S Mennin; Richard G Heimberg; Cynthia L Turk; David M Fresco
Journal:  Behav Res Ther       Date:  2004-12-10

6.  Interference resolution in major depression.

Authors:  Jutta Joormann; Derek Evan Nee; Marc G Berman; John Jonides; Ian H Gotlib
Journal:  Cogn Affect Behav Neurosci       Date:  2010-03       Impact factor: 3.282

7.  Efficacy of a cognitive-behavioral treatment for generalized anxiety disorder: evaluation in a controlled clinical trial.

Authors:  R Ladouceur; M J Dugas; M H Freeston; E Léger; F Gagnon; N Thibodeau
Journal:  J Consult Clin Psychol       Date:  2000-12

8.  A component analysis of cognitive-behavioral therapy for generalized anxiety disorder and the role of interpersonal problems.

Authors:  T D Borkovec; Michelle G Newman; Aaron L Pincus; Richard Lytle
Journal:  J Consult Clin Psychol       Date:  2002-04

Review 9.  A novel theory of experiential avoidance in generalized anxiety disorder: a review and synthesis of research supporting a contrast avoidance model of worry.

Authors:  Michelle G Newman; Sandra J Llera
Journal:  Clin Psychol Rev       Date:  2011-01-26

10.  A pilot randomized trial of metacognitive therapy vs applied relaxation in the treatment of adults with generalized anxiety disorder.

Authors:  Adrian Wells; Mary Welford; Paul King; Costas Papageorgiou; Julie Wisely; Elizabeth Mendel
Journal:  Behav Res Ther       Date:  2010-01-04
View more
  33 in total

1.  Perseverate or decenter? Differential effects of metacognition on the relationship between parasympathetic inflexibility and symptoms of depression in a multi-wave study.

Authors:  Jonathan P Stange; Jessica L Hamilton; David M Fresco; Lauren B Alloy
Journal:  Behav Res Ther       Date:  2017-07-17

Review 2.  All together now: utilizing common functional change principles to unify cognitive behavioral and mindfulness-based therapies.

Authors:  David M Fresco; Douglas S Mennin
Journal:  Curr Opin Psychol       Date:  2018-10-30

3.  Emotion regulation therapy for cancer caregivers-an open trial of a mechanism-targeted approach to addressing caregiver distress.

Authors:  Allison J Applebaum; Aliza A Panjwani; Kara Buda; Mia S O'Toole; Michael A Hoyt; Adam Garcia; David M Fresco; Douglas S Mennin
Journal:  Transl Behav Med       Date:  2020-05-20       Impact factor: 3.046

4.  Change in Decentering Mediates Improvement in Anxiety in Mindfulness-Based Stress Reduction for Generalized Anxiety Disorder.

Authors:  Elizabeth A Hoge; Eric Bui; Elizabeth Goetter; Donald J Robinaugh; Rebecca A Ojserkis; David M Fresco; Naomi M Simon
Journal:  Cognit Ther Res       Date:  2014-10-14

5.  Distress intolerance as a moderator of the relationship between daily stressors and affective symptoms: Tests of incremental and prospective relationships.

Authors:  Richard J Macatee; Brian J Albanese; Nicholas P Allan; Norman B Schmidt; Jesse R Cougle
Journal:  J Affect Disord       Date:  2016-07-19       Impact factor: 4.839

6.  When worry may be good for you: Worry severity and limbic-prefrontal functional connectivity in late-life generalized anxiety disorder.

Authors:  M Wu; D S Mennin; M Ly; H T Karim; L Banihashemi; D L Tudorascu; H J Aizenstein; C Andreescu
Journal:  J Affect Disord       Date:  2019-07-05       Impact factor: 4.839

7.  Inflexibility as a Vulnerability to Depression: A Systematic Qualitative Review.

Authors:  Jonathan P Stange; Lauren B Alloy; David M Fresco
Journal:  Clin Psychol (New York)       Date:  2017-06-13

8.  The Translational Potential of Neuroimaging Genomic Analyses To Diagnosis And Treatment In The Mental Disorders.

Authors:  Jiayu Chen; Jingyu Liu; Vince D Calhoun
Journal:  Proc IEEE Inst Electr Electron Eng       Date:  2019-05-09       Impact factor: 10.961

Review 9.  A neurobehavioral account for decentering as the salve for the distressed mind.

Authors:  Anthony P King; David M Fresco
Journal:  Curr Opin Psychol       Date:  2019-02-22

Review 10.  Treating comorbid anxiety and depression: Psychosocial and pharmacological approaches.

Authors:  Jeremy D Coplan; Cindy J Aaronson; Venkatesh Panthangi; Younsuk Kim
Journal:  World J Psychiatry       Date:  2015-12-22
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.