Literature DB >> 25945791

Correction: Evaluation of Hs-CRP Levels and Interleukin 18 (-137G/C) Promoter Polymorphism in Risk Prediction of Coronary Artery Disease in First Degree Relatives.

Rajesh Kumar G, Mrudula Spurthi K, Kishore Kumar G, Mohanalatha Kurapati, Saraswati M, Mohini Aiyengar T, Chiranjeevi P, Srilatha Reddy G, Nivas S, Kaushik P, Sanjib Sahu K, Surekha Rani H.   

Abstract

Entities:  

Year:  2015        PMID: 25945791      PMCID: PMC4422673          DOI: 10.1371/journal.pone.0127609

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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In Table 2, there are errors in the “Dominant,” “Recessive,” “Overdominant,” and “Allele frequency” rows. Please view the corrected table below.
Table 2

Genotype distribution of IL 18–137 G/C polymorphism in Controls, CAD patients and FDRS (N = 700).

ModelGenotypeControls N = 300 n (%)CAD N = 300 n (%)CAD Odds RatioFDRS N = 100 n (%)FDRS Odds Ratio
χ2Odds ratio (95% CI)p-Valueχ2Odds ratio(95% CI)p-Value
Co-dominant GG 176(58.7)168(56)0.00110.9965(65)2.3410.12
GC 105(35)102(34)1.02 (0.72–1.44)25(25)0.64 (0.38–1.09)
CC 19(6.3)30(10)1.81.65 (0.90–3.05)0.1710(10)2.381.43 (0.63–3.23)0.12
Dominant GG 176(58.7)168(56)0.331.120.5665(65)10.760.31
GC-CC 124(41.3)132(44)(0.81–1.54)35(35)(0.48–1.22)
Recessive GG-GC 281(93.7)270(90)2.221.640.1390(90)11.640.31
CC 19(6.3)30(10)(0.90–2.99)10(10)(0.74–3.66)
Overdominant GG-CC 195(65)198(66)0.020.960.8675(75)2.90.620.08
GC 105(35)102(34)(0.68–1.34)25(25)(0.37–1.03)
Log-Additive - - - -- - - -- - - -- - - -1.170.23- - - -- - - -0.930.71
(0.91–1.50)(0.65–1.34)
Allele frequency G 457(76)438(73)1.421.1820.23155(78)0.080.920.77
C 143(24)162(27)(0.91–1.53)45(22)(0.6295–1.354)
Minor allele frequency C 0.240.27- - - -0.22- - - -
HWE (p-value) 0.530.019- - - -0.007- - - -
Additionally, in Fig 3, the line “Analysis of promoter binding site for IL-8 polymorphism” is erroneously included. Please view the corrected figure here.
Fig 3

Analysis of Promoter binding site for IL -18-137 G/C Polymorphism.

  1 in total

1.  Evaluation of Hs-CRP levels and interleukin 18 (-137G/C) promoter polymorphism in risk prediction of coronary artery disease in first degree relatives.

Authors:  Rajesh Kumar G; Mrudula Spurthi K; Kishore Kumar G; Mohanalatha Kurapati; Saraswati M; Mohini Aiyengar T; Chiranjeevi P; Srilatha Reddy G; Nivas S; Kaushik P; Sanjib Sahu K; Surekha Rani H
Journal:  PLoS One       Date:  2015-03-30       Impact factor: 3.240

  1 in total

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