| Literature DB >> 25944286 |
Steffen Buschschlüter1, Jörn von Eicken2, Christian Koch3, Helmut Höh2.
Abstract
Phacoemulsification, a common treatment for cataract, is accompanied by cell damage at the corneal endothelium. Thermal exposure during treatment has been considered a reason for this damage, but a thorough experimental and theoretical assessment of the local temperature distribution inside the eye had not yet been conducted. Measurements in porcine eyes and a finite-element simulation enabled such an assessment and localized the highest temperature rise very close to the probe. The results described in this study indicate that a distance of 1 mm between the probe and the endothelium should be maintained during treatment as a safety margin, especially when fluid flow is blocked. The highest measured temperature rise with surgically reasonable system settings and unblocked fluid flow was 1.11°C. The finite-element simulation described here is able to calculate the temperature rise at the endothelium and could serve as a tool for comparing arbitrary surgical situations with respect to thermal exposure of the endothelium.Entities:
Keywords: Cell damage; Endothelium; Finite-element simulation; Phacoemulsification; Temperature increase
Mesh:
Year: 2015 PMID: 25944286 DOI: 10.1016/j.ultrasmedbio.2015.03.028
Source DB: PubMed Journal: Ultrasound Med Biol ISSN: 0301-5629 Impact factor: 2.998