Literature DB >> 25942704

IBD. Fishing for missing heritability in IBD.

Michael Pack1.   

Abstract

A genetic predisposition to IBD is widely accepted; however IBD heritability is dependent on more than the simple additive risk of genetic variants. In a new study using zebrafish, convincing evidence is presented that alterations in the epigenetic regulation of TNF might contribute to the "missing heritability" of IBD.

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Year:  2015        PMID： 25942704     DOI： 10.1038/nrgastro.2015.72

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN： 1759-5045            Impact factor:   46.802


  10 in total

1.  Update on the heritability of inflammatory bowel disease: the importance of twin studies.

Authors:  Steven R Brant
Journal:  Inflamm Bowel Dis       Date:  2011-01       Impact factor: 5.325

Review 2.  Natural history and complications of IBD.

Authors:  Morten H Vatn
Journal:  Curr Gastroenterol Rep       Date:  2009-12

3.  UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma.

Authors:  Raksha Mudbhary; Yujin Hoshida; Yelena Chernyavskaya; Vinitha Jacob; Augusto Villanueva; M Isabel Fiel; Xintong Chen; Kensuke Kojima; Swan Thung; Roderick T Bronson; Anja Lachenmayer; Kate Revill; Clara Alsinet; Ravi Sachidanandam; Anal Desai; Sucharita SenBanerjee; Chinweike Ukomadu; Josep M Llovet; Kirsten C Sadler
Journal:  Cancer Cell       Date:  2014-01-30       Impact factor: 31.743

4.  Epigenetic control of intestinal barrier function and inflammation in zebrafish.

Authors:  Lindsay Marjoram; Ashley Alvers; M Elizabeth Deerhake; Jennifer Bagwell; Jamie Mankiewicz; Jordan L Cocchiaro; Rebecca W Beerman; Jason Willer; Kaelyn D Sumigray; Nicholas Katsanis; David M Tobin; John F Rawls; Mary G Goll; Michel Bagnat
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-17       Impact factor: 11.205

5.  The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.

Authors:  Yuuki Obata; Yukihiro Furusawa; Takaho A Endo; Jafar Sharif; Daisuke Takahashi; Koji Atarashi; Manabu Nakayama; Satoshi Onawa; Yumiko Fujimura; Masumi Takahashi; Tomokatsu Ikawa; Takeshi Otsubo; Yuki I Kawamura; Taeko Dohi; Shoji Tajima; Hiroshi Masumoto; Osamu Ohara; Kenya Honda; Shohei Hori; Hiroshi Ohno; Haruhiko Koseki; Koji Hase
Journal:  Nat Immunol       Date:  2014-04-28       Impact factor: 25.606

Review 6.  Could a swimming creature inform us on intestinal diseases? Lessons from zebrafish.

Authors:  Ye Yang; Sarah Tomkovich; Christian Jobin
Journal:  Inflamm Bowel Dis       Date:  2014-05       Impact factor: 5.325

7.  TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase.

Authors:  Randolph P Matthews; Kristin Lorent; Rafael Mañoral-Mobias; Yuehua Huang; Weilong Gong; Ian V J Murray; Ian A Blair; Michael Pack
Journal:  Development       Date:  2009-03       Impact factor: 6.868

Review 8.  DNA methylation in inflammatory bowel disease and beyond.

Authors:  Daren Low; Atsushi Mizoguchi; Emiko Mizoguchi
Journal:  World J Gastroenterol       Date:  2013-08-28       Impact factor: 5.742

Review 9.  Missing heritability of common diseases and treatments outside the protein-coding exome.

Authors:  Wolfgang Sadee; Katherine Hartmann; Michał Seweryn; Maciej Pietrzak; Samuel K Handelman; Grzegorz A Rempala
Journal:  Hum Genet       Date:  2014-08-09       Impact factor: 4.132

10.  Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:  Luke Jostins; Stephan Ripke; Rinse K Weersma; Richard H Duerr; Dermot P McGovern; Ken Y Hui; James C Lee; L Philip Schumm; Yashoda Sharma; Carl A Anderson; Jonah Essers; Mitja Mitrovic; Kaida Ning; Isabelle Cleynen; Emilie Theatre; Sarah L Spain; Soumya Raychaudhuri; Philippe Goyette; Zhi Wei; Clara Abraham; Jean-Paul Achkar; Tariq Ahmad; Leila Amininejad; Ashwin N Ananthakrishnan; Vibeke Andersen; Jane M Andrews; Leonard Baidoo; Tobias Balschun; Peter A Bampton; Alain Bitton; Gabrielle Boucher; Stephan Brand; Carsten Büning; Ariella Cohain; Sven Cichon; Mauro D'Amato; Dirk De Jong; Kathy L Devaney; Marla Dubinsky; Cathryn Edwards; David Ellinghaus; Lynnette R Ferguson; Denis Franchimont; Karin Fransen; Richard Gearry; Michel Georges; Christian Gieger; Jürgen Glas; Talin Haritunians; Ailsa Hart; Chris Hawkey; Matija Hedl; Xinli Hu; Tom H Karlsen; Limas Kupcinskas; Subra Kugathasan; Anna Latiano; Debby Laukens; Ian C Lawrance; Charlie W Lees; Edouard Louis; Gillian Mahy; John Mansfield; Angharad R Morgan; Craig Mowat; William Newman; Orazio Palmieri; Cyriel Y Ponsioen; Uros Potocnik; Natalie J Prescott; Miguel Regueiro; Jerome I Rotter; Richard K Russell; Jeremy D Sanderson; Miquel Sans; Jack Satsangi; Stefan Schreiber; Lisa A Simms; Jurgita Sventoraityte; Stephan R Targan; Kent D Taylor; Mark Tremelling; Hein W Verspaget; Martine De Vos; Cisca Wijmenga; David C Wilson; Juliane Winkelmann; Ramnik J Xavier; Sebastian Zeissig; Bin Zhang; Clarence K Zhang; Hongyu Zhao; Mark S Silverberg; Vito Annese; Hakon Hakonarson; Steven R Brant; Graham Radford-Smith; Christopher G Mathew; John D Rioux; Eric E Schadt; Mark J Daly; Andre Franke; Miles Parkes; Severine Vermeire; Jeffrey C Barrett; Judy H Cho
Journal:  Nature       Date:  2012-11-01       Impact factor: 49.962
  10 in total
  3 in total

1.  Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns.

Authors:  Nao Yamakawa; Jorick Vanbeselaere; Lan-Yi Chang; Shin-Yi Yu; Lucie Ducrocq; Anne Harduin-Lepers; Junichi Kurata; Kiyoko F Aoki-Kinoshita; Chihiro Sato; Kay-Hooi Khoo; Ken Kitajima; Yann Guerardel
Journal:  Nat Commun       Date:  2018-11-07       Impact factor: 14.919

Review 2.  Determinants of IBD Heritability: Genes, Bugs, and More.

Authors:  Williams Turpin; Ashleigh Goethel; Larbi Bedrani; Kenneth Croitoru Mdcm
Journal:  Inflamm Bowel Dis       Date:  2018-05-18       Impact factor: 5.325

Review 3.  Application of Zebrafish Models in Inflammatory Bowel Disease.

Authors:  Li Hanyang; Liu Xuanzhe; Chen Xuyang; Qiu Yujia; Fu Jiarong; Shen Jun; Ran Zhihua
Journal:  Front Immunol       Date:  2017-05-03       Impact factor: 7.561
  3 in total

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