Literature DB >> 25942282

A new furan derivative from an endophytic Aspergillus flavus of Cephalotaxus fortunei.

Yang-Min Ma1, Cong-Cong Ma1, Ting Li1, Jun Wang1.   

Abstract

A new furan derivative named 5-acetoxymethylfuran-3-carboxylic acid (2), together with a known furan compound, 5-hydroxymethylfuran-3-carboxylic acid (1), were isolated from the fermentation of Aspergillus flavus, endophytic fungi in Cephalotaxus fortunei. The structures of 1 and 2 were elucidated by NMR, IR, UV and MS data, as well as compared with literature data. The compounds 1 and 2 exhibited potent antibacterial activity against Staphylococcus aureus with MIC values of 31.3 and 15.6 μg/mL, respectively. The compound 2 showed moderate antioxidant activity.

Entities:  

Keywords:  5-acetoxymethylfuran-3-carboxylic acid; Aspergillus flavus; Cephalotaxus fortunei; furan derivative

Mesh：

Substances：

Year:  2015        PMID： 25942282     DOI： 10.1080/14786419.2015.1038262

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  8 in total

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  8 in total

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