[Hormone therapy in menopause can increase the risk of ovarian cancer].

Risk of ovarian cancer should be added to the list of adverse effects of hormone replacement therapy (HRT). However there is no need for change in clinical recommendations. The recommendation today is to prescribe the lowest dose and shortest time of HRT for menopausal symptom relief. Our clinical approach should be to include among other risk factors the risk of one extra case of ovarian cancer/1000 users for 5 years of HRT versus reduced quality of life without HRT for each woman.