Literature DB >> 25941619

Vitamin B6 improves the immunogenicity of cisplatin-induced cell death.

Fernando Aranda1, Norma Bloy1, Lorenzo Galluzzi1, Guido Kroemer2, Laura Senovilla3.   

Abstract

We have recently demonstrated that pyridoxine, a precursor of vitamin B6, increases the immunogenicity of non-small cell lung carcinoma (NSCLC) cells succumbing to cisplatin (cis-diamminedichloroplatinum(II), CDDP). Accordingly, pyridoxine promoted the antineoplastic activity of CDDP in NSCLC-bearing mice only in the presence of an intact immune system. These findings may have implications for the development of novel strategies to circumvent CDDP resistance.

Entities:  

Keywords:  ATP; CDDP, cis-diamminedichloroplatinum(II); HMGB1; NSCLC, non-small cell lung carcinoma; PDXK; PDXK, pyridoxal kinase; PN, pyridoxine; apoptosis; autophagy; calreticulin; endoplasmic reticulum stress

Year:  2014        PMID： 25941619      PMCID： PMC4292417          DOI： 10.4161/21624011.2014.955685

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

1.  Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer.

Authors:  F Aranda; N Bloy; J Pesquet; B Petit; K Chaba; A Sauvat; O Kepp; N Khadra; D Enot; C Pfirschke; M Pittet; L Zitvogel; G Kroemer; L Senovilla
Journal:  Oncogene       Date:  2014-07-28       Impact factor: 9.867

2.  Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress.

Authors:  I Martins; O Kepp; F Schlemmer; S Adjemian; M Tailler; S Shen; M Michaud; L Menger; A Gdoura; N Tajeddine; A Tesniere; L Zitvogel; G Kroemer
Journal:  Oncogene       Date:  2010-12-13       Impact factor: 9.867

Review 3.  Molecular mechanisms of cisplatin resistance.

Authors:  L Galluzzi; L Senovilla; I Vitale; J Michels; I Martins; O Kepp; M Castedo; G Kroemer
Journal:  Oncogene       Date:  2011-09-05       Impact factor: 9.867

Review 4.  Immunogenic cell death in cancer therapy.

Authors:  Guido Kroemer; Lorenzo Galluzzi; Oliver Kepp; Laurence Zitvogel
Journal:  Annu Rev Immunol       Date:  2012-11-12       Impact factor: 28.527

Review 5.  Effects of vitamin B6 metabolism on oncogenesis, tumor progression and therapeutic responses.

Authors:  L Galluzzi; E Vacchelli; J Michels; P Garcia; O Kepp; L Senovilla; I Vitale; G Kroemer
Journal:  Oncogene       Date:  2013-01-21       Impact factor: 9.867

6.  Vitamin B6 metabolism influences the intracellular accumulation of cisplatin.

Authors:  Lorenzo Galluzzi; Sabrina Marsili; Ilio Vitale; Laura Senovilla; Judith Michels; Pauline Garcia; Erika Vacchelli; Etienne Chatelut; Maria Castedo; Guido Kroemer
Journal:  Cell Cycle       Date:  2012-02-01       Impact factor: 4.534

Review 7.  Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance.

Authors:  Laurence Zitvogel; Lorenzo Galluzzi; Mark J Smyth; Guido Kroemer
Journal:  Immunity       Date:  2013-07-25       Impact factor: 31.745

Review 8.  The resurgence of platinum-based cancer chemotherapy.

Authors:  Lloyd Kelland
Journal:  Nat Rev Cancer       Date:  2007-07-12       Impact factor: 60.716

9.  Prognostic impact of vitamin B6 metabolism in lung cancer.

Authors:  Lorenzo Galluzzi; Ilio Vitale; Laura Senovilla; Ken André Olaussen; Guillaume Pinna; Tobias Eisenberg; Aïcha Goubar; Isabelle Martins; Judith Michels; Gueorgui Kratassiouk; Didac Carmona-Gutierrez; Marie Scoazec; Erika Vacchelli; Frederic Schlemmer; Oliver Kepp; Shensi Shen; Maximilien Tailler; Mireia Niso-Santano; Eugenia Morselli; Alfredo Criollo; Sandy Adjemian; Mohamed Jemaà; Kariman Chaba; Claire Pailleret; Mickaël Michaud; Federico Pietrocola; Nicolas Tajeddine; Thibault de La Motte Rouge; Natalia Araujo; Nadya Morozova; Thomas Robert; Hugues Ripoche; Frederic Commo; Benjamin Besse; Pierre Validire; Pierre Fouret; Angélique Robin; Nicolas Dorvault; Philippe Girard; Sébastien Gouy; Patricia Pautier; Nora Jägemann; Ann-Christin Nickel; Sabrina Marsili; Caroline Paccard; Nicolas Servant; Philippe Hupé; Carmen Behrens; Parviz Behnam-Motlagh; Kimitoshi Kohno; Isabelle Cremer; Diane Damotte; Marco Alifano; Oivind Midttun; Per Magne Ueland; Vladimir Lazar; Philippe Dessen; Hans Zischka; Etienne Chatelut; Maria Castedo; Frank Madeo; Emmanuel Barillot; Juergen Thomale; Ignacio Ivan Wistuba; Catherine Sautès-Fridman; Laurence Zitvogel; Jean-Charles Soria; Annick Harel-Bellan; Guido Kroemer
Journal:  Cell Rep       Date:  2012-07-26       Impact factor: 9.423

Review 10.  Systems biology of cisplatin resistance: past, present and future.

Authors:  L Galluzzi; I Vitale; J Michels; C Brenner; G Szabadkai; A Harel-Bellan; M Castedo; G Kroemer
Journal:  Cell Death Dis       Date:  2014-05-29       Impact factor: 8.469
  10 in total
  9 in total

Review 1.  The function and mechanism of HMGB1 in lung cancer and its potential therapeutic implications.

Authors:  Lei Wu; Lili Yang
Journal:  Oncol Lett       Date:  2018-03-08       Impact factor: 2.967

2.  Induction of Immunogenic Cell Death of Esophageal Squamous Cell Carcinoma by 5-Fluorouracil and Cisplatin.

Authors:  Junya Nishimura; Sota Deguchi; Hiroaki Tanaka; Yoshihito Yamakoshi; Mami Yoshii; Tatsuro Tamura; Takahiro Toyokawa; Shigeru Lee; Kazuya Muguruma; Masaichi Ohira
Journal:  In Vivo       Date:  2021 Mar-Apr       Impact factor: 2.155

3.  Calreticulin expression: Interaction with the immune infiltrate and impact on survival in patients with ovarian and non-small cell lung cancer.

Authors:  Gautier Stoll; Kristina Iribarren; Judith Michels; Alexandra Leary; Laurence Zitvogel; Isabelle Cremer; Guido Kroemer
Journal:  Oncoimmunology       Date:  2016-06-09       Impact factor: 8.110

Review 4.  Combinatorial strategies for the induction of immunogenic cell death.

Authors:  Lucillia Bezu; Ligia C Gomes-de-Silva; Heleen Dewitte; Karine Breckpot; Jitka Fucikova; Radek Spisek; Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
Journal:  Front Immunol       Date:  2015-04-24       Impact factor: 7.561

5.  Chemosensitization strategies for the treatment of lung cancer.

Authors:  Laura Senovilla; Guido Kroemer
Journal:  Oncoscience       Date:  2015-08-20

6.  Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors.

Authors:  Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncotarget       Date:  2017-01-24

Review 7.  Autophagy, autophagy-associated adaptive immune responses and its role in hematologic malignancies.

Authors:  Liangshun You; Shenhe Jin; Li Zhu; Wenbin Qian
Journal:  Oncotarget       Date:  2017-02-14

Review 8.  Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response.

Authors:  Roger Gilabert-Oriol; Gemma M Ryan; Ada W Y Leung; Natalie S Firmino; Kevin L Bennewith; Marcel B Bally
Journal:  Int J Mol Sci       Date:  2018-09-26       Impact factor: 5.923

9.  MicroRNA339 Targeting PDXK Improves Motor Dysfunction and Promotes Neurite Growth in the Remote Cortex Subjected to Spinal Cord Transection.

Authors:  Liu-Lin Xiong; Yan-Xia Qin; Qiu-Xia Xiao; Yuan Jin; Mohammed Al-Hawwas; Zheng Ma; You-Cui Wang; Visar Belegu; Xin-Fu Zhou; Lu-Lu Xue; Ruo-Lan Du; Jia Liu; Xue Bai; Ting-Hua Wang
Journal:  Front Cell Dev Biol       Date:  2020-07-21
  9 in total

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