Literature DB >> 25941576

Inhibition of MYC in macrophages: tumor vs inflammation-related diseases.

Emilio Cano-Ramos1, Begoña Lavin2, Oscar M Pello1.   

Abstract

Inhibition of MYC has been postulated as one of the most promising anti-tumoral therapies. However, if some anti-inflammatory cells express MYC, would an anti-tumoral treatment targeting MYC facilitate subsequent inflammation-related disorders?

Entities:  

Keywords:  MYC; inflammation; macrophages; tumor

Year:  2014        PMID： 25941576      PMCID： PMC4292312          DOI： 10.4161/21624011.2014.956013

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

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Authors:  Antonio Sica; Alberto Mantovani
Journal:  J Clin Invest       Date:  2012-03-01       Impact factor: 14.808

2.  Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology.

Authors:  Oscar M Pello; Maria De Pizzol; Massimiliano Mirolo; Laura Soucek; Luca Zammataro; Angelo Amabile; Andrea Doni; Manuela Nebuloni; Lamorna B Swigart; Gerard I Evan; Alberto Mantovani; Massimo Locati
Journal:  Blood       Date:  2011-11-08       Impact factor: 22.113

3.  Nitric oxide prevents aortic neointimal hyperplasia by controlling macrophage polarization.

Authors:  Begoña Lavin; Monica Gómez; Oscar M Pello; Borja Castejon; Maria J Piedras; Marta Saura; Carlos Zaragoza
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4.  The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Authors:  Ruoning Wang; Christopher P Dillon; Lewis Zhichang Shi; Sandra Milasta; Robert Carter; David Finkelstein; Laura L McCormick; Patrick Fitzgerald; Hongbo Chi; Joshua Munger; Douglas R Green
Journal:  Immunity       Date:  2011-12-23       Impact factor: 31.745

5.  Therapeutic Targeting of Myc.

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Journal:  Genes Cancer       Date:  2010-06

6.  Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc.

Authors:  Vanesa Muncan; Owen J Sansom; Leon Tertoolen; Toby J Phesse; Harry Begthel; Elena Sancho; Alicia M Cole; Alex Gregorieff; Ignacio Moreno de Alboran; Hans Clevers; Alan R Clarke
Journal:  Mol Cell Biol       Date:  2006-09-05       Impact factor: 4.272

7.  Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences.

Authors:  Fernando O Martinez; Laura Helming; Ronny Milde; Audrey Varin; Barbro N Melgert; Christina Draijer; Benjamin Thomas; Marco Fabbri; Anjali Crawshaw; Ling Pei Ho; Nick H Ten Hacken; Viviana Cobos Jiménez; Neeltje A Kootstra; Jörg Hamann; David R Greaves; Massimo Locati; Alberto Mantovani; Siamon Gordon
Journal:  Blood       Date:  2013-01-04       Impact factor: 22.113

8.  In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities.

Authors:  Oscar M Pello; Raphael Chèvre; Damya Laoui; Alba De Juan; Fidel Lolo; María Jesús Andrés-Manzano; Manuel Serrano; Jo A Van Ginderachter; Vicente Andrés
Journal:  PLoS One       Date:  2012-09-20       Impact factor: 3.240

9.  Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma.

Authors:  Stefanie Regine Dannenmann; Julia Thielicke; Martina Stöckli; Claudia Matter; Lotta von Boehmer; Virginia Cecconi; Thomas Hermanns; Lukas Hefermehl; Peter Schraml; Holger Moch; Alexander Knuth; Maries van den Broek
Journal:  Oncoimmunology       Date:  2013-03-01       Impact factor: 8.110

10.  Role of c-MYC in tumor-associated macrophages and cancer progression.

Authors:  Oscar M Pello; Vicente Andrés
Journal:  Oncoimmunology       Date:  2013-02-01       Impact factor: 8.110
  10 in total
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  3 in total

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