Literature DB >> 25940220

A naphthalene diimide dyad for fluorescence switch-on detection of G-quadruplexes.

F Doria1, A Oppi, F Manoli, S Botti, N Kandoth, V Grande, I Manet, M Freccero.   

Abstract

A non-fluorescent naphthalene diimide (NDI) dimer, conjugating red and blue NDI dyes, becomes red/NIR emitting upon G-quadruplex binding. The fluorescence lifetime which is significantly different for the complexes, the G-quadruplex/dimer and the weakly emitting ds-DNA/dimer is the key feature for the development of new rationally engineered G-quadruplex sensors.

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Year:  2015        PMID： 25940220     DOI： 10.1039/c5cc01536g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

Review 1.  Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual-Color Flag.

Authors:  Elisabete Oliveira; Emilia Bértolo; Cristina Núñez; Viviane Pilla; Hugo M Santos; Javier Fernández-Lodeiro; Adrian Fernández-Lodeiro; Jamila Djafari; José Luis Capelo; Carlos Lodeiro
Journal:  ChemistryOpen       Date:  2017-11-07       Impact factor: 2.911

2.  More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand.

Authors:  Michela Zuffo; Aurore Guédin; Emma-Dune Leriche; Filippo Doria; Valentina Pirota; Valérie Gabelica; Jean-Louis Mergny; Mauro Freccero
Journal:  Nucleic Acids Res       Date:  2018-11-02       Impact factor: 16.971

3.  Synthesis, Characterization, and Crystal Structures of Imides Condensed with p-Phenylamino(Phenyl) Amine and Fluorescence Property.

Authors:  Jing Zhang; Huaibo Ma
Journal:  Materials (Basel)       Date:  2019-06-10       Impact factor: 3.623

4.  Visualization of Parallel G-Quadruplexes in Cells with a Series of New Developed Bis(4-aminobenzylidene)acetone Derivatives.

Authors:  Chenlin Yang; Rui Hu; Qian Li; Shuang Li; Junfeng Xiang; Xudong Guo; Shuangqing Wang; Yi Zeng; Yi Li; Guoqiang Yang
Journal:  ACS Omega       Date:  2018-09-04

5.  Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-Quadruplexes.

Authors:  Rosalba Perrone; Filippo Doria; Elena Butovskaya; Ilaria Frasson; Silvia Botti; Matteo Scalabrin; Sara Lago; Vincenzo Grande; Matteo Nadai; Mauro Freccero; Sara N Richter
Journal:  J Med Chem       Date:  2015-12-08       Impact factor: 7.446

6.  A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging.

Authors:  F Doria; M Nadai; M Zuffo; R Perrone; M Freccero; S N Richter
Journal:  Chem Commun (Camb)       Date:  2017-02-14       Impact factor: 6.222

7.  Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model.

Authors:  Martina Tassinari; Michela Zuffo; Matteo Nadai; Valentina Pirota; Adriana Carolina Sevilla Montalvo; Filippo Doria; Mauro Freccero; Sara N Richter
Journal:  Nucleic Acids Res       Date:  2020-05-21       Impact factor: 16.971

Review 8.  Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands.

Authors:  Valentina Pirota; Matteo Nadai; Filippo Doria; Sara N Richter
Journal:  Molecules       Date:  2019-01-24       Impact factor: 4.411

9.  Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography.

Authors:  Chiara Platella; Valentina Pirota; Domenica Musumeci; Federica Rizzi; Sara Iachettini; Pasquale Zizza; Annamaria Biroccio; Mauro Freccero; Daniela Montesarchio; Filippo Doria
Journal:  Int J Mol Sci       Date:  2020-03-13       Impact factor: 5.923
  9 in total

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