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Literature DB >> 25939167

The mRNA expression of the human 1,25-dihydroxyvitamin D3 receptor and the c-myc protooncogene in cultured human keratinocytes.

Abstract

The human vitamin D receptor mRNA expression in preconfluent human cultured keratinocytes was upregulated by treatment of these cells with 10(-8) M 1,25(OH)2D3 for 24 hours. Additionally, human c-myc mRNA expression was decreased in a dose dependent manner by 1,25(OH)2D3 in both preconfluent and confluent cultured human keratinocytes.

Entities: Chemical Gene Species

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Year: 1994 PMID： 25939167 DOI： 10.1007/bf02631442

Source DB: PubMed Journal: In Vitro Cell Dev Biol Anim ISSN： 1071-2690 Impact factor: 2.416

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References

39 in total

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The mRNA expression of the human 1,25-dihydroxyvitamin D3 receptor and the c-myc protooncogene in cultured human keratinocytes.

Review 1. Actions of 1 alpha,25-dihydroxyvitamin D3 on normal, psoriatic, and promoted epidermal keratinocytes.

2. Microinjected c-myc as a competence factor.

3. Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.

4. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene.

5. Treatment of psoriasis by the topical application of the novel cholecalciferol analogue calcipotriol (MC 903)

6. Psoriasis and vitamin D3. A review of our experience.

7. The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma.

8. The effects of chronic prednisone administration on intestinal receptors for 1,25-dihydroxyvitamin D3 in the dog.

9. Regulation of 1,25-dihydroxyvitamin D3 receptors by vitamin D analogs in cultured mammalian cells.

10. Interaction of 1,25-dihydroxyvitamin-D3 with keratinocytes and fibroblasts from skin of normal subjects and a subject with vitamin-D-dependent rickets, type II: a model for study of the mode of action of 1,25-dihydroxyvitamin D3.