| Literature DB >> 25938946 |
Yaping Wang1, Ying Lu2, Yong Zhang3, Zemin Ning4, Yan Li2, Qiang Zhao2, Hengyun Lu2, Rong Huang1, Xiaoqin Xia1, Qi Feng2, Xufang Liang5, Kunyan Liu2, Lei Zhang2, Tingting Lu2, Tao Huang2, Danlin Fan2, Qijun Weng2, Chuanrang Zhu2, Yiqi Lu2, Wenjun Li2, Ziruo Wen2, Congcong Zhou2, Qilin Tian2, Xiaojun Kang6, Mijuan Shi1, Wanting Zhang1, Songhun Jang7, Fukuan Du1, Shan He5, Lanjie Liao1, Yongming Li1, Bin Gui1, Huihui He1, Zhen Ning1, Cheng Yang6, Libo He1, Lifei Luo1, Rui Yang8, Qiong Luo8, Xiaochun Liu3, Shuisheng Li3, Wen Huang3, Ling Xiao3, Haoran Lin3, Bin Han2, Zuoyan Zhu1.
Abstract
The grass carp is an important farmed fish, accounting for ∼16% of global freshwater aquaculture, and has a vegetarian diet. Here we report a 0.9-Gb draft genome of a gynogenetic female adult and a 1.07-Gb genome of a wild male adult. Genome annotation identified 27,263 protein-coding gene models in the female genome. A total of 114 scaffolds consisting of 573 Mb are anchored on 24 linkage groups. Divergence between grass carp and zebrafish is estimated to have occurred 49-54 million years ago. We identify a chromosome fusion in grass carp relative to zebrafish and report frequent crossovers between the grass carp X and Y chromosomes. We find that transcriptional activation of the mevalonate pathway and steroid biosynthesis in liver is associated with the grass carp's adaptation from a carnivorous to an herbivorous diet. We believe that the grass carp genome could serve as an initial platform for breeding better-quality fish using a genomic approach.Entities:
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Year: 2015 PMID： 25938946 DOI： 10.1038/ng.3280
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330