| Literature DB >> 25938172 |
Sonia Merino1, Cristina Martín1, Kostas Kostarelos, Maurizio Prato2, Ester Vázquez1.
Abstract
Considerable progress in the synthesis and technology of hydrogels makes these materials attractive structures for designing controlled-release drug delivery systems. In particular, this review highlights the latest advances in nanocomposite hydrogels as drug delivery vehicles. The inclusion/incorporation of nanoparticles in three-dimensional polymeric structures is an innovative means for obtaining multicomponent systems with diverse functionality within a hybrid hydrogel network. Nanoparticle-hydrogel combinations add synergistic benefits to the new 3D structures. Nanogels as carriers for cancer therapy and injectable gels with improved self-healing properties have also been described as new nanocomposite systems.Entities:
Keywords: external field; hydrogel; nanocomposite; nanogel; nanoparticle; on-demand delivery; self-healing; stimuli-response
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Year: 2015 PMID: 25938172 DOI: 10.1021/acsnano.5b01433
Source DB: PubMed Journal: ACS Nano ISSN: 1936-0851 Impact factor: 15.881