Literature DB >> 25937500

Five new cycloartane triterpenoids from Beesia calthifolia.

Dan-Jun Zheng1, Jing Zhou1, Qian Liu1, Wei Yao2, Min-Zhe Zhang1, Bai-Hao Shao1, Jian-Xia Mo1, Chang-Xin Zhou1, Li-She Gan3.   

Abstract

Phytochemical study on rhizomes of Beesia calthifolia resulted in the isolation of five new (1-5) and three known (6-8) cycloartane triterpenoids possessing a hemiketal or ketal group at C-24 from the EtOAc fraction of 95% ethanol extract. Their structures were determined by spectroscopic and chemical methods, especially HRMS and 2D NMR techniques. Compounds 3 and 4 showed potential hepatoprotective activities against D-galactosamine induced human hepatic L02 cell damage.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  2D NMR; Beesia calthifolia; Cycloartane triterpenoid; Hepatoprotective activity

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Year:  2015        PMID: 25937500     DOI: 10.1016/j.fitote.2015.04.017

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  1 in total

Review 1.  Antitumor Profile of Carbon-Bridged Steroids (CBS) and Triterpenoids.

Authors:  Valery M Dembitsky; Tatyana A Gloriozova; Vladimir V Poroikov
Journal:  Mar Drugs       Date:  2021-06-03       Impact factor: 5.118

  1 in total

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