Literature DB >> 25936295

Is there any role for the hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?

S De Carolis1, A Botta1, S Salvi1, E di Pasquo2, G Del Sordo1, C Garufi1, A Lanzone1, M P De Carolis3.   

Abstract

The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels.
Copyright © 2015 Elsevier B.V. All rights reserved.

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Year:  2015        PMID: 25936295     DOI: 10.1016/j.autrev.2015.04.010

Source DB:  PubMed          Journal:  Autoimmun Rev        ISSN: 1568-9972            Impact factor:   9.754


  12 in total

1.  Pregnancy Outcome in Women with Obstetric and Thrombotic Antiphospholipid Syndrome-A Retrospective Analysis and a Review of Additional Treatment in Pregnancy.

Authors:  Karoline Mayer-Pickel; Katharina Eberhard; Uwe Lang; Mila Cervar-Zivkovic
Journal:  Clin Rev Allergy Immunol       Date:  2017-08       Impact factor: 8.667

2.  What is the best time to assess the antiphospholipid antibodies (aPL) profile to better predict the obstetric outcome in antiphospholipid syndrome (APS) patients?

Authors:  Jose Omar Latino; Sebastián Udry; Silvia Perés Wingeyer; Diego Fernández Romero; Paula Micone; Gabriela de Larrañaga
Journal:  Immunol Res       Date:  2018-10       Impact factor: 2.829

3.  Treatment of Refractory/High-Risk Pregnancies With Antiphospholipid Syndrome: A Systematic Review of the Literature.

Authors:  Ariela Hoxha; Daniela Tormene; Elena Campello; Paolo Simioni
Journal:  Front Pharmacol       Date:  2022-05-19       Impact factor: 5.988

Review 4.  Lymphocyte Disturbances in Primary Antiphospholipid Syndrome and Application to Venous Thromboembolism Follow-Up.

Authors:  Laurent Simonin; Elisabeth Pasquier; Christophe Leroyer; Divi Cornec; Julie Lemerle; Boutahar Bendaoud; Sophie Hillion; Jacques-Olivier Pers; Francis Couturaud; Yves Renaudineau
Journal:  Clin Rev Allergy Immunol       Date:  2017-08       Impact factor: 8.667

Review 5.  Management of rheumatoid arthritis during pregnancy: challenges and solutions.

Authors:  Megan L Krause; Ashima Makol
Journal:  Open Access Rheumatol       Date:  2016-03-23

Review 6.  Review: Hydroxychloroquine and Chloroquine for Treatment of SARS-CoV-2 (COVID-19).

Authors:  Katelyn A Pastick; Elizabeth C Okafor; Fan Wang; Sarah M Lofgren; Caleb P Skipper; Melanie R Nicol; Matthew F Pullen; Radha Rajasingham; Emily G McDonald; Todd C Lee; Ilan S Schwartz; Lauren E Kelly; Sylvain A Lother; Oriol Mitjà; Emili Letang; Mahsa Abassi; David R Boulware
Journal:  Open Forum Infect Dis       Date:  2020-04-15       Impact factor: 3.835

Review 7.  Immunosuppressive Treatment in Antiphospholipid Syndrome: Is It Worth It?

Authors:  Ilaria Mormile; Francescopaolo Granata; Alessandra Punziano; Amato de Paulis; Francesca Wanda Rossi
Journal:  Biomedicines       Date:  2021-02-01

Review 8.  Comparison of treatments for the prevention of fetal growth restriction in obstetric antiphospholipid syndrome: a systematic review and network meta-analysis.

Authors:  Maria Letizia Urban; Alessandra Bettiol; Irene Mattioli; Alfredo Vannacci; Elena Silvestri; Domenico Prisco; Giacomo Emmi; Gerardo Di Scala; Laura Avagliano; Niccolò Lombardi; Giada Crescioli; Gianni Virgili; Caterina Serena; Federico Mecacci; Claudia Ravaldi
Journal:  Intern Emerg Med       Date:  2021-01-21       Impact factor: 3.397

9.  Anti-Phosphatidylserine/Prothrombin Antibodies in Healthy Women with Unexplained Recurrent Pregnancy Loss.

Authors:  Daniel E Pleguezuelo; Oscar Cabrera-Marante; Magdalena Abad; Edgard Alfonso Rodriguez-Frias; Laura Naranjo; Alicia Vazquez; Olga Villar; Francisco Javier Gil-Etayo; Manuel Serrano; Alfredo Perez-Rivilla; Laura de la Fuente-Bitaine; Antonio Serrano
Journal:  J Clin Med       Date:  2021-05-13       Impact factor: 4.241

10.  Hepatic infarction in a pregnant woman with antiphospholipid syndrome and triple antibody positivity: A case report focusing on catastrophic antiphospholipid syndrome.

Authors:  Ji-Hye Kim; Cheonga Yee; Jin-Yi Kuk; Suk-Joo Choi; Soo-Young Oh; Cheong-Rae Roh; Jong-Hwa Kim
Journal:  Obstet Gynecol Sci       Date:  2016-09-13
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