Literature DB >> 25935449

Prophylactic surgery in familial adenomatous polyposis (FAP)--a single surgeon's short- and long-term experience with hand-assisted proctocolectomy and smaller J-pouches.

Ralph Schneider1, Claudia Schneider, Anne Dalchow, Christian Jakobeit, Gabriela Möslein.   

Abstract

PURPOSE: Prophylactic proctocolectomy with an ileoanal neo-reservoir is the established procedure in non-attenuated familial adenomatous polyposis (FAP). Traditionally, the ileal J-pouch is created by doubling 15 cm of the terminal ileum. Pouch inlet problems are not infrequently encountered in longer pouches. On this rationale, this series reports on the functional outcome and quality of life (QoL) following standardized construction of a shorter J-pouch with a limb of 8-9 cm length.
METHODS: All patients of a single-surgeon series with FAP who underwent hand-assisted laparoscopic proctocolectomy and small ileal pouch-anal anastomosis as the primary procedure between 10/2005 and 04/2010 and responded to the questionnaire were included and retrospectively analyzed.
RESULTS: A total of 46 patients (78 %) out of the consecutive series who underwent operation in this period were included in the study. After a mean follow-up of 38 months, 40/46 patients (87 %) did not report any incontinence and 3 patients (6.5 %) complained about occasional nocturnal incontinence (3 failed to answer this question). The mean stool frequency per 24 h was 6.25. No significant difference was encountered between the QoL outcome of our patients versus the German normative population. Comparable results were achieved in a study analyzing the long-term results in FAP patients with a 15-cm pouch.
CONCLUSIONS: Smaller, 8-9 cm J-pouches show excellent functional results both in short- and in long-term results. The hand-assisted procedure was safe and no conversions were required. QoL is equal to a normative population, as it is in a series of patients with larger J-pouches.

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Year:  2015        PMID: 25935449     DOI: 10.1007/s00384-015-2223-9

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  53 in total

1.  The correlation between quality of life and functional outcome in ulcerative colitis patients after proctocolectomy ileal pouch anal anastomosis.

Authors:  E Carmon; A Keidar; A Ravid; G Goldman; M Rabau
Journal:  Colorectal Dis       Date:  2003-05       Impact factor: 3.788

2.  Comparison of outcomes of ileal pouch-anal anastomosis for familial adenomatous polyposis with and without previous ileorectal anastomosis.

Authors:  A C von Roon; P P Tekkis; R E Lovegrove; K F Neale; R K S Phillips; S K Clark
Journal:  Br J Surg       Date:  2008-04       Impact factor: 6.939

3.  Surgical management of multiple polyposis. The problem of cancer in the retained bowel segment.

Authors:  C G Moertel; J R Hill; M A Adson
Journal:  Arch Surg       Date:  1970-04

4.  Quality of life after prophylactic colectomy and ileorectal anastomosis in patients with familial adenomatous polyposis.

Authors:  J M Church; V W Fazio; I C Lavery; J R Oakley; J Milsom; E McGannon
Journal:  Dis Colon Rectum       Date:  1996-12       Impact factor: 4.585

5.  Proctocolectomy without ileostomy for ulcerative colitis.

Authors:  A G Parks; R J Nicholls
Journal:  Br Med J       Date:  1978-07-08

6.  Long-term follow-up after colectomy and ileorectal anastomosis in familial adenomatous polyposis coli. Is there still a place for the procedure?

Authors:  J F Slors; F C den Hartog Jager; J W Trum; C W Taat; W H Brummelkamp
Journal:  Hepatogastroenterology       Date:  1989-04

Review 7.  Pouchitis: pathophysiology and treatment.

Authors:  T Kühbacher; S Schreiber; N Runkel
Journal:  Int J Colorectal Dis       Date:  1998       Impact factor: 2.571

8.  Female fecundity before and after operation for familial adenomatous polyposis.

Authors:  K Ø Olsen; S Juul; S Bülow; H J Järvinen; A Bakka; J Björk; T Oresland; S Laurberg
Journal:  Br J Surg       Date:  2003-02       Impact factor: 6.939

9.  Manometric and functional comparison of ileal pouch anal anastomosis with and without anal manipulation.

Authors:  W Tuckson; I Lavery; V Fazio; J Oakley; J Church; J Milsom
Journal:  Am J Surg       Date:  1991-01       Impact factor: 2.565

10.  The prognosis of clinical course and the analysis of the frequency of the inflammation and dysplasia in the intestinal J-pouch at the patients after restorative proctocolectomy due to FAP.

Authors:  Tomasz Banasiewicz; Ryszard Marciniak; Elzbieta Kaczmarek; Piotr Krokowicz; Jacek Paszkowski; Aleksandra Lozynska-Nelke; Piotr Gronek; Andrzej Plawski; Michal Drews
Journal:  Int J Colorectal Dis       Date:  2011-05-11       Impact factor: 2.571

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  1 in total

Review 1.  Surgical considerations in FAP-related pouch surgery: Could we do better?

Authors:  Gabriela Möslein
Journal:  Fam Cancer       Date:  2016-07       Impact factor: 2.375

  1 in total

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