Literature DB >> 25934972

Effectiveness and efficiency of platelet rich plasma in the treatment of diabetic ulcers.

Raquel Cobos1, Felipe Aizpuru, Naiara Parraza, Eduardo Anitua, Gorka Orive.   

Abstract

"There is a growing body of evidence suggesting that wound healing in chronic diabetic foot ulcers is growth factor dependent, and that the therapeutic delivery of these growth factors to wounds topically, has the potential ability to accelerate wound healing in conjunction with conventional wound care". There is, however, confusion about the utility of platelet rich plasma because the studies that have evaluated them use a wide range of products (different platelet and leukocyte concentrations, different techniques and frequencies of application, very heterogeneous simple, and different endpoints) making almost impossible to compare data and draw conclusions. In this study, we have analyzed the different platelet rich plasma products from a new perspective: cost-efficiency. According to our data, we observe that platelet rich plasma is a cost-effective option that allows faster healing of ulcers, and that should be taken into account in patients with long evolution ulcers.

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Mesh:

Year:  2015        PMID: 25934972     DOI: 10.2174/138920101607150427111926

Source DB:  PubMed          Journal:  Curr Pharm Biotechnol        ISSN: 1389-2010            Impact factor:   2.837


  5 in total

Review 1.  A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification.

Authors:  Rubina Alves; Ramon Grimalt
Journal:  Skin Appendage Disord       Date:  2017-07-06

2.  Pilot study: Autologous platelet-rich plasma used in a topical cream for facial rejuvenation.

Authors:  Zoe Diana Draelos; Lawrence A Rheins; Shaun Wootten; Robert S Kellar; Robert B Diller
Journal:  J Cosmet Dermatol       Date:  2019-07-26       Impact factor: 2.696

3.  Membrane of Plasma Rich in Growth Factors in Primary Pterygium Surgery Compared to Amniotic Membrane Transplantation and Conjunctival Autograft.

Authors:  Miriam Idoipe; Borja de la Sen-Corcuera; Ronald M Sánchez-Ávila; Carmen Sánchez-Pérez; María Satué; Antonio Sánchez-Pérez; Gorka Orive; Francisco Muruzabal; Eduardo Anitua; Luis Pablo
Journal:  J Clin Med       Date:  2021-12-06       Impact factor: 4.241

4.  High-Throughput Proteomic Analysis of Human Dermal Fibroblast Response to Different Blood Derivatives: Autologous Topical Serum Derived from Plasma Rich in Growth Factors (PRGF) versus Leukocyte- and Platelet-Rich Plasma (L-PRP).

Authors:  Eduardo Anitua; Ander Pino; Mikel Azkargorta; Felix Elortza; Roberto Prado
Journal:  Biomolecules       Date:  2022-07-19

5.  Current concepts for the evaluation and management of diabetic foot ulcers.

Authors:  Andreas F Mavrogenis; Panayiotis D Megaloikonomos; Thekla Antoniadou; Vasilios G Igoumenou; Georgios N Panagopoulos; Leonidas Dimopoulos; Konstantinos G Moulakakis; George S Sfyroeras; Andreas Lazaris
Journal:  EFORT Open Rev       Date:  2018-09-27
  5 in total

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