Nicolas Koutlidis1, Luc Joyeux2, Nathalie Méjean3, Emmanuel Sapin4. 1. Department of Paediatric Surgery, Children's Hospital of Dijon, University Medical Center, Dijon, France. Electronic address: nicolas.koutlidis@chu-dijon.fr. 2. Department of Paediatric Surgery, Children's Hospital of Dijon, University Medical Center, Dijon, France. Electronic address: luc.joyeux@chu-dijon.fr. 3. Department of Radiology, Children's Hospital of Dijon, University Medical Center, 21079, Dijon, France. Electronic address: nathalie.mejean@chu-dijon.fr. 4. Department of Paediatric Surgery, Children's Hospital of Dijon, University Medical Center, Dijon, France. Electronic address: emmanuel.sapin@chu-dijon.fr.
Abstract
OBJECTIVE: The widespread use of renal ultrasonography has resulted in simple renal cysts (SRC) being discovered with increasing frequency in routine pediatric urological practice. Management of SRC, however, remains controversial. Most SRC are asymptomatic, are diagnosed incidentally, and have no clinical consequence. Our goal was to focus on management strategies for SRC in children with the support of our experience and a review of the literature. MATERIALS AND METHODS: A literature review was made of SRC in children since 1950, analyzing epidemiologic data, diagnosis, and management. In addition, a retrospective multicenter study was conducted from 1998 to 2009. Patients included presented with a unique SRC. Data recorded were patient characteristics (age, gender), symptoms, imaging features of the cyst (size, side, pole, and location), type of management, and long-term outcomes. To focus on management, two groups of patients were defined: primary surgical management and primary conservative management consisting of clinical and US follow-up. Our results were compared with the literature. RESULTS: Thirty-six cases were included. Fifteen patients were symptomatic. Comparing the two groups, long-term outcomes were similar. The only significant factors were preoperative (age of the patient, diameter and location of the cyst): the bigger the cyst, the more likely it was to be exorenal, and the greater the likelihood that surgery would be performed (p = 0.006). Symptoms were not a significant indicator for surgery. CONCLUSION: According to the literature and our experience, and considering the benign natural history of SRC and the similar outcomes whatever the treatment, primary conservative management is recommended for all cases. Surgery should be restricted to symptomatic large compressive cysts, increase in cyst size on follow-up, and uncertain diagnosis. Percutaneous cyst aspiration with sclerotherapy has not yet been used enough to ascertain its safety, and requires prospective evaluation.
OBJECTIVE: The widespread use of renal ultrasonography has resulted in simple renal cysts (SRC) being discovered with increasing frequency in routine pediatric urological practice. Management of SRC, however, remains controversial. Most SRC are asymptomatic, are diagnosed incidentally, and have no clinical consequence. Our goal was to focus on management strategies for SRC in children with the support of our experience and a review of the literature. MATERIALS AND METHODS: A literature review was made of SRC in children since 1950, analyzing epidemiologic data, diagnosis, and management. In addition, a retrospective multicenter study was conducted from 1998 to 2009. Patients included presented with a unique SRC. Data recorded were patient characteristics (age, gender), symptoms, imaging features of the cyst (size, side, pole, and location), type of management, and long-term outcomes. To focus on management, two groups of patients were defined: primary surgical management and primary conservative management consisting of clinical and US follow-up. Our results were compared with the literature. RESULTS: Thirty-six cases were included. Fifteen patients were symptomatic. Comparing the two groups, long-term outcomes were similar. The only significant factors were preoperative (age of the patient, diameter and location of the cyst): the bigger the cyst, the more likely it was to be exorenal, and the greater the likelihood that surgery would be performed (p = 0.006). Symptoms were not a significant indicator for surgery. CONCLUSION: According to the literature and our experience, and considering the benign natural history of SRC and the similar outcomes whatever the treatment, primary conservative management is recommended for all cases. Surgery should be restricted to symptomatic large compressive cysts, increase in cyst size on follow-up, and uncertain diagnosis. Percutaneous cyst aspiration with sclerotherapy has not yet been used enough to ascertain its safety, and requires prospective evaluation.
Authors: Michail Vagias; Guillaume Chanoit; Loretta J Bubenik-Angapen; Erin A Gibson; Hilde de Rooster; Ameet Singh; Valery F Scharf; Janet A Grimes; Mandy L Wallace; Anne Kummeling; James A Flanders; Georgios Evangelou; Ronan A Mullins Journal: BMC Vet Res Date: 2022-06-20 Impact factor: 2.792